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MIR29B1 and PLOD1
Data Source:
BioGRID
(unspecified method)
MIR29B1
PLOD1
Description
microRNA 29b-1
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Extracellular Exosome
Extracellular Vesicle
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum Membrane
Extracellular Exosome
Catalytic Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Iron Ion Binding
Protein Binding
Procollagen-lysine 5-dioxygenase Activity
L-ascorbic Acid Binding
Procollagen Glucosyltransferase Activity
Biological Process
Negative Regulation Of Cytokine-mediated Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Type III Interferon Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of MAPK Cascade
Regulation Of DNA Methylation
Positive Regulation Of Fat Cell Differentiation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Protein Secretion
Negative Regulation Of Protein Kinase B Signaling
Regulation Of Blood Vessel Remodeling
Negative Regulation Of Circulating Fibrinogen Levels
Negative Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Virus
Negative Regulation Of Interleukin-32 Production
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Aorta Morphogenesis
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Matrix Metallopeptidase Secretion
Positive Regulation Of Metalloendopeptidase Activity
Regulation Of Epithelium Regeneration
Negative Regulation Of Metallopeptidase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Osteoblast Differentiation
Negative Regulation Of Intestinal Epithelial Cell Development
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Response To Hypoxia
Protein O-linked Glycosylation
Epidermis Development
Peptidyl-lysine Hydroxylation
Protein Phosphopantetheinylation
Pathways
Collagen biosynthesis and modifying enzymes
Drugs
Ascorbic acid
Diseases
Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
Nevo syndrome
GWAS
Pancreatic cancer (
25086665
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Diastolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Moyamoya disease (
29273593
)
Platelet count (
27863252
)
Plateletcrit (
27863252
)
Tuberculosis (
29036319
)
Interacting Genes
72 interacting genes:
APOBEC3B
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
RBFOX2
RBM14
RBM4
RBM47
RBMS2
RTCB
SF3B1
SF3B3
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
TRIM71
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
40 interacting genes:
MIR1-2
MIR10B
MIR122
MIR128-2
MIR141
MIR143
MIR15A
MIR15B
MIR17
MIR18A
MIR18B
MIR199A2
MIR19A
MIR19B1
MIR206
MIR20A
MIR214
MIR221
MIR222
MIR29B1
MIR34A
MIR34B
MIR363
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
USP4
Entrez ID
407024
5351
HPRD ID
01086
Ensembl ID
ENSG00000283797
ENSG00000083444
Uniprot IDs
Q02809
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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