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DHX36 and MIR222
Data Source:
BioGRID
(unspecified method)
DHX36
MIR222
Description
DEAH-box helicase 36
microRNA 222
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Perikaryon
Extracellular Exosome
Extracellular Space
Extracellular Vesicle
Molecular Function
Magnesium Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
G-quadruplex RNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
MRNA 3'-UTR Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
MRNA 3'-UTR AU-rich Region Binding
Histone Deacetylase Binding
MRNA 5'-UTR Binding
G-quadruplex DNA Binding
Telomerase RNA Binding
Pre-miRNA Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Ossification
Positive Regulation Of Myeloid Dendritic Cell Cytokine Production
Regulation Of Transcription By RNA Polymerase III
Spermatogenesis
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Negative Regulation Of Translation
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Telomere Maintenance
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Cellular Response To Heat
Cellular Response To UV
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Regulation Of MRNA Stability
G-quadruplex DNA Unwinding
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Defense Response To Virus
Positive Regulation Of Cardioblast Differentiation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Dendritic Spine Morphogenesis
3'-UTR-mediated MRNA Destabilization
Telomerase RNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Hematopoietic Progenitor Cell Differentiation
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spermatogenesis
Cellular Response To Arsenite Ion
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Intracellular MRNA Localization
Positive Regulation Of Cytoplasmic Translation
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Angiogenesis
Negative Regulation Of Interleukin-21 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Apoptotic Process
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Cell Adhesion Molecule Production
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Body mass index (
29273807
)
Response to cognitive-behavioural therapy in anxiety disorder (
31123309
)
Interacting Genes
71 interacting genes:
DUX4
IL7R
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
TLR1
ZFP36
75 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RBFOX2
RBM14
RBM4
RBMS2
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
170506
407007
HPRD ID
09918
Ensembl ID
ENSG00000174953
ENSG00000207725
Uniprot IDs
Q9H2U1
PDB IDs
2N16
2N21
6Q6R
Enriched GO Terms of Interacting Partners
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