KRT85 and KRT35

Data Source:
BioGRID (two hybrid)

		KRT85	KRT35
Description		keratin 85	keratin 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Keratin Filament	Extracellular Space Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Epidermis Development Keratinization Cornification	Anatomical Structure Morphogenesis Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Ectodermal dysplasia, pure hair-nail type (HNED)
GWAS		Body mass index ( 28552196)
Interacting Genes		26 interacting genes: ALOX12 CLIC3 CREB5 CYSRT1 GNE HAPLN2 KLHL38 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LHX8 OTX1 TAB2 ZNF655	87 interacting genes: ABI3 ATG9A BCAS2 C1orf109 C21orf58 CCDC120 CCDC185 CCDC196 CCHCR1 CD33 CTSZ DMRT3 DTNB EFCAB3 ENKD1 EXOSC5 FAM221B FRS3 HAPLN2 HCK HDAC4 HGS HOXA1 HOXC8 KCTD9 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 LONRF1 MAPKBP1 MCRS1 MYO15B OIP5 OTX1 PKN1 POU4F2 PRPF18 PRPF31 PRR35 RUNX1T1 SCNM1 SHC3 SLC43A2 SMARCE1 SMYD1 TAPBPL TBC1D21 TBC1D30 TBC1D7 TCEANC TCHP TEKT4 TEPSIN TLE5 TRIM29 TSG101 TXLNA TXLNB UBASH3A USP2 VPS9D1 ZNF417 ZNF446
Entrez ID		3891	3886
HPRD ID		04139	04138
Ensembl ID		ENSG00000135443	ENSG00000197079
Uniprot IDs		B7Z7N3 F5GYI5 P78386	Q92764
PDB IDs
Enriched GO Terms of Interacting Partners?
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