KRT85 and KLHL38

Data Source:
BioGRID (two hybrid)

		KRT85	KLHL38
Description		keratin 85	kelch like family member 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Keratin Filament
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Ectodermal dysplasia, pure hair-nail type (HNED)
GWAS		Body mass index ( 28552196)	Atrial fibrillation ( 29892015) Carotid intima media thickness (mean) ( 31801372) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 25055868) Heel bone mineral density ( 30598549) PR interval ( 32439900) QRS duration ( 30012220) Systolic blood pressure ( 30578418)
Interacting Genes		26 interacting genes: ALOX12 CLIC3 CREB5 CYSRT1 GNE HAPLN2 KLHL38 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LHX8 OTX1 TAB2 ZNF655	88 interacting genes: ADAMTSL4 ADRA2C AGR2 ASB12 BHLHB9 BLZF1 C11orf1 CCDC33 CERCAM CFP CTAG1A CTAG1B CYSRT1 DMAC2L ECM1 FTO GOLGA6A GSC2 HDHD3 IKZF3 KLHL20 KRT27 KRT31 KRT34 KRT35 KRT38 KRT39 KRT40 KRT85 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP4-11 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LHX3 LHX4 MAGEA6 MDFI MEOX2 MGAT5B MKRN3 MORN3 NBPF19 NOTCH2NLA OIP5 PAX5 PBX4 PFDN5 PLSCR4 POF1B POU2AF1 RGS20 RSPO4 SLC15A2 SPRY4 TACC3 TADA2A TCF4 TEKT1 TEKT5 TENT5B TEPSIN TIMM10B TRAF1 TRIB3 TRIM42 TRIM54 TRIM69 TXNDC11 UBE3A USHBP1 WFDC5 WWOX YPEL3 ZNF341
Entrez ID		3891	340359
HPRD ID		04139	19276
Ensembl ID		ENSG00000135443	ENSG00000175946
Uniprot IDs		B7Z7N3 F5GYI5 P78386	Q2WGJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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