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KRT31 and AQP1
Data Source:
BioGRID
(two hybrid)
KRT31
AQP1
Description
keratin 31
aquaporin 1 (Colton blood group)
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytosol
Intermediate Filament
Extracellular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Biological Process
Cytoskeleton Organization
Epidermis Development
Keratinization
Cornification
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Pathways
Keratinization
Formation of the cornified envelope
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Brown vs. black hair color (
30531825
)
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
356 interacting genes:
A1CF
ABI2
ABI3
ABL1
ACTR10
AGR2
AGXT
AIMP2
AKR7A3
ALDH3B1
AMOT
AMOTL2
ANKRD36BP1
ANKS1A
AQP1
AQP5
ARHGAP35
ARID3A
ARMC7
ARSJ
ASMTL
ASPSCR1
ATG9A
ATN1
ATXN7L1
ATXN7L2
AVPI1
B4GALT7
BAD
BCAS2
BEX1
BEX2
BFSP2
BHLHA9
BRME1
BTC
BYSL
C19orf73
C1orf109
C1orf216
C2CD6
C3
C5orf49
C5orf60
CA6
CARD9
CATIP
CATSPER1
CBX8
CCDC112
CCDC116
CCDC120
CCDC146
CCDC17
CCDC187
CCDC196
CCDC198
CCDC93
CCER1
CCHCR1
CCNC
CD33
CDC20B
CDK18
CDKN1A
CDKN2C
CDR2L
CEP57
CEP57L1
CEP70
CFAP206
CFAP53
CHCHD2
CHRNG
CLCNKA
CLDN19
CLDN2
CLEC18A
CNNM3
CNTF
COA5
COMT
COX5A
COX5B
CRACR2A
CREB5
CRH
CTSG
CXCL16
CYSRT1
DEF6
DGCR6L
DHX37
DMRT3
DOCK2
DTNB
EIF4E2
EIF4G1
ENKD1
EPDR1
EXOC8
EXOSC5
FADS2
FAM110A
FAM124B
FAM50B
FAM71C
FAM74A4
FAM90A1
FARS2
FBF1
FBXW5
FGF16
FKBP1B
FOXB1
FRS3
GAD1
GADD45GIP1
GEM
GFAP
GFOD1
GLRX3
GNAI2
GNE
GNG10
GNG5
GOLGA6L2
GPS2
GSTP1
HAPLN2
HAUS1
HBA1
HBA2
HBZ
HCK
HDAC4
HGS
HNRNPLL
HOXA1
HOXB5
HS6ST1
HSD3B7
HSF4
HSPA12B
HSPD1
HYAL2
ICAM4
IL16
INPP5D
INPP5K
INSR
ITGB2
ITGB4
ITGB5
JOSD1
KCTD9
KDM1A
KIAA1217
KIFC3
KLC1
KLC4
KLHL38
KLK8
KRT1
KRT2
KRT20
KRT3
KRT4
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT75
KRT76
KRT77
KRT78
KRT79
KRT8
KRT80
KRT81
KRT82
KRT83
KRT85
KRT86
KRTAP4-12
KRTAP5-6
KRTAP9-2
KRTAP9-3
LATS1
LCE1B
LCE3C
LCE3D
LCE3E
LCE4A
LENG1
LIF
LIN37
LINC00526
LMF2
LMNTD2
LMO3
LMO4
LONRF1
LRRC41
MAB21L2
MAP3K7CL
MAPKBP1
MARK4
MID2
MOS
MRPL40
MSRB3
MTA1
MXD3
MXI1
MYOM1
NAV1
NAXD
NEK6
NODAL
NPBWR2
NTAQ1
NUDT16L1
NUFIP2
OTUB2
OTX1
P2RX7
P3H3
PBX3
PDE4DIP
PDGFRB
PGAP6
PGLS
PHC2
PHLDA1
PIN1
PKN1
PKN3
PKP2
PLEKHN1
POLDIP3
POU4F2
POU4F3
PPP1R18
PPP1R32
PRF1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRPH
PRR19
PRR35
PSMA1
PSMB1
PSMC5
PSMG2
PSPC1
PTGER3
PTPMT1
R3HDM2
RAB33A
RADIL
RAMAC
RCOR3
RHPN1
RIBC1
RPS19BP1
RPUSD3
RSPH14
RTP5
SAMD11
SCNM1
SEC14L4
SEMA4C
SHC3
SHFL
SHISA6
SIRPA
SLC15A3
SLC23A1
SLC25A42
SLC25A6
SMARCD1
SMARCE1
SMCP
SMG9
SNAI1
SNRNP25
SPATA24
SPG21
SPON2
SPRING1
SPRY1
SRSF2
SSX2IP
STK16
TACO1
TAPBPL
TCEANC
TEAD4
TEPSIN
TEX28
TEX33
TFAP2D
THAP7
TLE5
TMEM106C
TMEM174
TMEM231
TMSB4X
TRAF4
TRIML2
TROAP
TSEN54
TSG101
TSHZ3
TSNAX
TTC23
TTC9C
TXLNA
TYK2
UACA
UBASH3A
USHBP1
USP2
UTP23
UXT
VASN
VPS9D1
WDR25
WFDC6
ZDHHC1
ZFHX3
ZFYVE21
ZGPAT
ZIC1
ZNF124
ZNF148
ZNF20
ZNF250
ZNF414
ZNF417
ZNF446
ZNF564
ZNF569
ZNF572
ZNF587
ZNF688
ZNF69
ZNF835
ZNRF2P1
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
Entrez ID
3881
358
HPRD ID
03047
00140
Ensembl ID
ENSG00000094796
ENSG00000240583
Uniprot IDs
Q15323
A0A024RA31
P29972
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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