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KRT16 and KRT2
Data Source:
BioGRID
(two hybrid)
KRT16
KRT2
Description
keratin 16
keratin 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Intermediate Filament
Extracellular Exosome
Cornified Envelope
Extracellular Space
Nucleus
Cytosol
Intermediate Filament
Membrane
Keratin Filament
Extracellular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Cytoskeletal Protein Binding
Structural Constituent Of Skin Epidermis
Biological Process
Morphogenesis Of An Epithelium
Inflammatory Response
Cytoskeleton Organization
Aging
Keratinocyte Differentiation
Negative Regulation Of Cell Migration
Keratinization
Hair Cycle
Innate Immune Response
Intermediate Filament Cytoskeleton Organization
Keratinocyte Migration
Establishment Of Skin Barrier
Cornification
Keratinocyte Development
Epidermis Development
Peptide Cross-linking
Keratinization
Keratinocyte Activation
Keratinocyte Proliferation
Intermediate Filament Organization
Positive Regulation Of Epidermis Development
Keratinocyte Migration
Cornification
Pathways
Keratinization
Formation of the cornified envelope
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Zinc acetate
Zinc
Copper
Anthralin
Zinc acetate
Diseases
Non-epidermolytic palmoplantar keratoderma (NEPPK)
Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
Ichthyosis bullosa of Siemens
GWAS
Interacting Genes
56 interacting genes:
AMOT
ARFIP2
C1orf109
C1orf216
CARD9
CCDC146
CCDC17
CCHCR1
CCNC
CDK18
CYTH4
EPM2AIP1
GAS8
GNG10
HGS
KIFC3
KLC4
KRT1
KRT2
KRT3
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT76
KRT78
KRT79
KRT8
KRT80
KRT81
KRT83
KRT85
KRT86
LMO1
LNX1
MBD3
PKN1
POLL
PPP1R18
PRKAA2
PRPH
PUS10
SEMA4C
SGF29
SMARCD1
SMARCE1
SNAPIN
TCHP
TSG101
TTC23
TXLNB
USHBP1
15 interacting genes:
EVPL
KRT13
KRT15
KRT16
KRT19
KRT25
KRT27
KRT31
KRT33B
KRT35
KRT36
KRT38
KRT40
SIRPA
SMAD3
Entrez ID
3868
3849
HPRD ID
01018
02560
Ensembl ID
ENSG00000186832
ENSG00000172867
Uniprot IDs
P08779
P35908
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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