KRT2 and KRT33B

Data Source:
BioGRID (two hybrid)

		KRT2	KRT33B
Description		keratin 2	keratin 33B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding
	Biological Process	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration Cornification	Aging Keratinization Hair Cycle Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper Anthralin Zinc acetate
Diseases		Ichthyosis bullosa of Siemens
GWAS
Interacting Genes		15 interacting genes: EVPL KRT13 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT35 KRT36 KRT38 KRT40 SIRPA SMAD3	56 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT6B KRT6C KRT71 KRT72 KRT75 KRT78 KRT79 KRT8 KRT80 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C
Entrez ID		3849	3884
HPRD ID		02560	04136
Ensembl ID		ENSG00000172867	ENSG00000131738
Uniprot IDs		P35908	Q14525
PDB IDs
Enriched GO Terms of Interacting Partners?
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