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KRT16 and CDK18
Data Source:
BioGRID
(two hybrid)
KRT16
CDK18
Description
keratin 16
cyclin dependent kinase 18
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Intermediate Filament
Extracellular Exosome
Cellular_component
Nucleus
Cytoplasm
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Morphogenesis Of An Epithelium
Inflammatory Response
Cytoskeleton Organization
Aging
Keratinocyte Differentiation
Negative Regulation Of Cell Migration
Keratinization
Hair Cycle
Innate Immune Response
Intermediate Filament Cytoskeleton Organization
Keratinocyte Migration
Establishment Of Skin Barrier
Cornification
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Regulation Of Cell Cycle
Pathways
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Zinc acetate
Diseases
Non-epidermolytic palmoplantar keratoderma (NEPPK)
Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Coronary artery disease in type 1 diabetes (
29695241
)
Interacting Genes
56 interacting genes:
AMOT
ARFIP2
C1orf109
C1orf216
CARD9
CCDC146
CCDC17
CCHCR1
CCNC
CDK18
CYTH4
EPM2AIP1
GAS8
GNG10
HGS
KIFC3
KLC4
KRT1
KRT2
KRT3
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT76
KRT78
KRT79
KRT8
KRT80
KRT81
KRT83
KRT85
KRT86
LMO1
LNX1
MBD3
PKN1
POLL
PPP1R18
PRKAA2
PRPH
PUS10
SEMA4C
SGF29
SMARCD1
SMARCE1
SNAPIN
TCHP
TSG101
TTC23
TXLNB
USHBP1
56 interacting genes:
AK8
APP
BLZF1
CBY2
CCDC102B
CCDC125
CCDC85B
CCDC88B
CCND3
CCNDBP1
CCNK
CEP76
EYA2
FSD2
GOLGA2
GOLGA6L9
GORASP2
HAP1
HMBOX1
HOMER3
HOOK2
INCA1
KIFC3
KRT15
KRT16
KRT31
KRT34
KRT40
KRT75
KRT86
LZTS2
MAD1L1
MID2
MIPOL1
MTUS2
NUTM1
PIBF1
PNMA1
PPFIA1
RABEP1
REL
SEC23A
TRAF1
TRAF2
TRIM27
TRIM50
TRIM54
TSGA10
TTC23
VPS28
VPS52
YWHAQ
ZNF426
ZNF438
ZNF774
ZRANB1
Entrez ID
3868
5129
HPRD ID
01018
01354
Ensembl ID
ENSG00000186832
ENSG00000117266
Uniprot IDs
P08779
A0A024R980
A0A024R996
Q07002
Q59G02
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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