KRT2 and KRT13

Data Source:
BioGRID (two hybrid, two hybrid)

		KRT2	KRT13
Description		keratin 2	keratin 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding
	Biological Process	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration Cornification	Cytoskeleton Organization Keratinization Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper Anthralin Zinc acetate
Diseases		Ichthyosis bullosa of Siemens	White sponge nevus
GWAS
Interacting Genes		15 interacting genes: EVPL KRT13 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT35 KRT36 KRT38 KRT40 SIRPA SMAD3	63 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT79 KRT8 LSM2 MOS MYH1 MYO15B NEFL PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688
Entrez ID		3849	3860
HPRD ID		02560	01016
Ensembl ID		ENSG00000172867	ENSG00000171401
Uniprot IDs		P35908	A1A4E9 P13646
PDB IDs
Enriched GO Terms of Interacting Partners?
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