TROAP and KRT8

Data Source:
BioGRID (pull down)

		TROAP	KRT8
Description		trophinin associated protein	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	Cell Adhesion	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Lanoteplase Copper
Diseases
GWAS			Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Prostate cancer ( 21743057)
Interacting Genes		20 interacting genes: BANP BYSL C19orf54 DYNLT1 DYRK1A DYRK1B GIGYF1 KRT31 KRT40 KRT8 MAPRE1 MAPRE3 NBPF19 NOTCH2NLA OIP5 SSC4D TP53BP2 TRAF2 TRIM23 TRO	49 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2
Entrez ID		10024	3856
HPRD ID		04849	01015
Ensembl ID		ENSG00000135451	ENSG00000170421
Uniprot IDs		F8W130 Q12815	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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