ARF5 and ARFIP2

Data Source:
HPRD (two hybrid, in vitro)

		ARF5	ARFIP2
Description		ADP ribosylation factor 5	ADP ribosylation factor interacting protein 2
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Type 2 diabetes ( 23532257)	Malaria ( 31844061)
Interacting Genes		14 interacting genes: ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DTX3 ERBB2 GGA1 GORAB IKBKG PIP5K1A RAB11A RAB11FIP3	61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARFIP1 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1
Entrez ID		381	23647
HPRD ID		00055	07209
Ensembl ID		ENSG00000004059	ENSG00000132254
Uniprot IDs		A4D0Z3 P84085	A0A087X1E4 B4DUZ3 B4DXH2 P53365
PDB IDs		2B6H	1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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