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ARFIP2 and ARF1
Data Source:
HPRD
(in vitro, two hybrid)
ARFIP2
ARF1
Description
ADP ribosylation factor interacting protein 2
ADP ribosylation factor 1
Image
GO Annotations
Cellular Component
Ruffle
Cytoplasm
Cytosol
Plasma Membrane
Cell Cortex
Trans-Golgi Network Membrane
Golgi Membrane
Cytoplasm
Late Endosome
Peroxisomal Membrane
Trans-Golgi Network
Cytosol
Plasma Membrane
Focal Adhesion
Postsynaptic Density
Sarcomere
COPI-coated Vesicle
Cell Leading Edge
Protein-containing Complex
Neuron Projection
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Protein Binding
GTP Binding
Phospholipid Binding
Protein Domain Specific Binding
GTP-dependent Protein Binding
Small GTPase Binding
Identical Protein Binding
Cadherin Binding
Phosphatidylinositol-4-phosphate Binding
Membrane Curvature Sensor Activity
Magnesium Ion Binding
RNA Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
Phospholipase D Activator Activity
Biological Process
Intracellular Protein Transport
Autophagy
Small GTPase Mediated Signal Transduction
Lamellipodium Assembly
Actin Cytoskeleton Organization
Ruffle Organization
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Receptor Internalization
Phosphatidylinositol Biosynthetic Process
Cellular Copper Ion Homeostasis
Intracellular Protein Transport
Actin Filament Organization
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Very-low-density Lipoprotein Particle Assembly
Interleukin-12-mediated Signaling Pathway
Positive Regulation Of Endocytosis
Positive Regulation Of Calcium Ion-dependent Exocytosis
Regulation Of Defense Response To Virus By Virus
Positive Regulation Of Protein Secretion
Regulation Of Catalytic Activity
Golgi To Transport Vesicle Transport
Long-term Synaptic Depression
Positive Regulation Of Dendritic Spine Development
Synaptic Vesicle Budding
Dendritic Spine Organization
Lysosomal Membrane Organization
Cellular Response To Virus
Postsynaptic Actin Cytoskeleton Organization
Positive Regulation Of Sodium Ion Transmembrane Transport
Positive Regulation Of Late Endosome To Lysosome Transport
Positive Regulation Of ER To Golgi Vesicle-mediated Transport
Regulation Of Phospholipid Metabolic Process
Mitotic Cleavage Furrow Ingression
Pathways
Retrograde transport at the Trans-Golgi-Network
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the Golgi membrane
Nef Mediated CD4 Down-regulation
trans-Golgi Network Vesicle Budding
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
Intra-Golgi traffic
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
1,3-Propanediol
Guanosine-3'-monophosphate-5'-diphosphate
Guanosine-5'-Triphosphate
Guanosine-5'-Diphosphate
Brefeldin A
Myristic acid
Glycerin
Diseases
GWAS
Malaria (
31844061
)
Adolescent idiopathic scoliosis (
31417091
)
Interacting Genes
61 interacting genes:
AGTRAP
AKT1
APP
ARF1
ARF3
ARF5
ARF6
ARFIP1
ARL1
BLOC1S2
C19orf25
CDKN2A
CDR1
CEP63
CMTM5
CYTH3
DGAT2L6
DMAP1
DTNBP1
FADS6
FSD2
GOLGA2
GSG1
HAUS1
HGS
ING5
ITGB3BP
ITSN1
KRT15
KRT16
LNX1
LY6D
MAL2
MIEF1
MIEF2
NDRG4
NRDE2
NUP62
PBX3
PKNOX2
PLP2
PPIF
RAC1
RAC2
RAC3
REEP5
REL
RND1
SCAMP1
SCAMP5
SDCBP
SH3GLB1
SMG9
SNX1
SOCS2
STAT3
SYP
TMEM255B
TRIM54
TTPA
USHBP1
47 interacting genes:
AGAP1
AGAP2
AP1B1
AP1G1
AP3B1
AP3D1
AP3S2
AP4E1
AP4M1
ARFGAP1
ARFIP1
ARFIP2
ARHGAP21
ASAP1
ASAP2
CHRM3
COPB1
COPE
COPG1
CYTH1
CYTH2
DUX4
EEF1G
ERBB2
GGA1
GGA2
GGA3
GORAB
GOSR2
HTR2A
INSR
KDELR1
MDM4
NOA1
NPM1
PICK1
PIP5K1A
PLD1
PLD2
PLEKHA8
PLIN2
RALA
SCYL1
TMED10
TMED2
TMEM106A
WBP11
Entrez ID
23647
375
HPRD ID
07209
00054
Ensembl ID
ENSG00000132254
ENSG00000143761
Uniprot IDs
A0A087X1E4
B4DUZ3
B4DXH2
P53365
A0A024R3Q0
P84077
PDB IDs
1I49
1I4D
1I4L
1I4T
4DCN
1HUR
1RE0
1U81
3O47
4HMY
6CM9
6CRI
6D83
6D84
6DFF
6FAE
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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