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ARFIP2 and PPIF
Data Source:
BioGRID
(two hybrid)
ARFIP2
PPIF
Description
ADP ribosylation factor interacting protein 2
peptidylprolyl isomerase F
Image
GO Annotations
Cellular Component
Ruffle
Cytoplasm
Cytosol
Plasma Membrane
Cell Cortex
Trans-Golgi Network Membrane
Cytoplasm
Mitochondrion
Mitochondrial Proton-transporting ATP Synthase Complex
Mitochondrial Permeability Transition Pore Complex
Mitochondrial Matrix
Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
GTP Binding
Phospholipid Binding
Protein Domain Specific Binding
GTP-dependent Protein Binding
Small GTPase Binding
Identical Protein Binding
Cadherin Binding
Phosphatidylinositol-4-phosphate Binding
Membrane Curvature Sensor Activity
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
Cyclosporin A Binding
Biological Process
Intracellular Protein Transport
Autophagy
Small GTPase Mediated Signal Transduction
Lamellipodium Assembly
Actin Cytoskeleton Organization
Ruffle Organization
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Protein Peptidyl-prolyl Isomerization
Response To Ischemia
Protein Folding
Apoptotic Mitochondrial Changes
Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism
Regulation Of Necrotic Cell Death
Negative Regulation Of ATPase Activity
Negative Regulation Of Apoptotic Process
Regulation Of Mitochondrial Membrane Permeability
Necroptotic Process
Cellular Response To Hydrogen Peroxide
Cellular Response To Arsenic-containing Substance
Cellular Response To Calcium Ion
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Oxidative Phosphorylation
Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death
Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death
Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Retrograde transport at the Trans-Golgi-Network
Drugs
Cyclosporine
Proline
Triglyme
Coumarin 120
Diseases
GWAS
Malaria (
31844061
)
Blood protein levels (
30072576
)
Height (
20881960
31562340
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
)
Mean platelet volume (
32888494
)
Metabolite levels (
23823483
)
Triglyceride levels (
32203549
)
Interacting Genes
61 interacting genes:
AGTRAP
AKT1
APP
ARF1
ARF3
ARF5
ARF6
ARFIP1
ARL1
BLOC1S2
C19orf25
CDKN2A
CDR1
CEP63
CMTM5
CYTH3
DGAT2L6
DMAP1
DTNBP1
FADS6
FSD2
GOLGA2
GSG1
HAUS1
HGS
ING5
ITGB3BP
ITSN1
KRT15
KRT16
LNX1
LY6D
MAL2
MIEF1
MIEF2
NDRG4
NRDE2
NUP62
PBX3
PKNOX2
PLP2
PPIF
RAC1
RAC2
RAC3
REEP5
REL
RND1
SCAMP1
SCAMP5
SDCBP
SH3GLB1
SMG9
SNX1
SOCS2
STAT3
SYP
TMEM255B
TRIM54
TTPA
USHBP1
19 interacting genes:
ABI2
AGTRAP
ARFIP2
BANP
CIDEB
CMTM5
FAM25A
FAM25C
FAM25G
FKBP7
MAGEA11
MUC1
PRB3
SERPINB5
SLC25A4
SYP
SYPL1
VDAC1
YIF1A
Entrez ID
23647
10105
HPRD ID
07209
06839
Ensembl ID
ENSG00000132254
ENSG00000108179
Uniprot IDs
A0A087X1E4
B4DUZ3
B4DXH2
P53365
A0A024QZS4
P30405
PDB IDs
1I49
1I4D
1I4L
1I4T
4DCN
2BIT
2BIU
2Z6W
3QYU
3R49
3R4G
3R54
3R56
3R57
3R59
3RCF
3RCG
3RCI
3RCK
3RCL
3RD9
3RDA
3RDB
3RDC
4J58
4J59
4J5A
4J5B
4J5C
4J5D
4J5E
4O8H
4O8I
4XNC
4ZSC
4ZSD
5A0E
5CBT
5CBU
5CBV
5CBW
5CCN
5CCQ
5CCR
5CCS
6R8L
6R8O
6R8W
6R9S
6R9U
6R9X
6RA1
6Y3E
6YBM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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