Description |
IL2 inducible T cell kinase |
transforming growth factor beta receptor 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Advanced age-related macular degeneration ( 26691988)
- Age-related macular degeneration ( 23455636)
- Asthma ( 31959851 32296059)
- Callous-unemotional behaviour ( 23874384)
- Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
- Dental caries ( 23064961)
- Epithelial ovarian cancer ( 25134534)
- Fractures (paediatric) ( 32742401)
- Gestational age at birth (maternal effect) ( 28877031)
- Refractive error ( 32231278)
- Spherical equivalent or myopia (age of diagnosis) ( 29808027)
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Interacting Genes |
34 interacting genes:
BLNK
BMX
BTK
CBL
CD28
DOK1
EGFR
ERBB2
ERBB3
ERBB4
FASLG
FGFR1
FYN
GAB1
GRB2
HNRNPK
IKBKG
KHDRBS1
KPNA2
LAT
LCK
LCP2
MET
PLCG1
PLCG2
PPIA
SH2D2A
SMAD4
SMURF1
SOCS1
SPRR2A
SRC
TGFBR1
WAS
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163 interacting genes:
ACVR1
ACVRL1
AMHR2
ANAPC5
AP2B1
ARHGAP15
ARHGAP31
ARHGEF6
ARL4D
ARL8B
ASH2L
AURKB
BAMBI
BMPR1B
BMPR2
BTBD2
CAV1
CD44
CDC20
CDC42EP4
CDK14
CDK17
CDK4
CDK6
CDKL1
CHN1
CHN2
CHUK
CLU
CSNK1A1
CSNK2A2
CTNNB1
CUL5
DAB2
DAPK2
DCAF12
DCAF6
DUSP13
EIF2AK4
ENC1
ENG
FANCL
FBXL12
FBXO34
FKBP1A
FKBP1B
FNTA
GNA13
GNB2
GNB3
IKBKB
ITK
KATNB1
KCNK18
KLHL1
KLHL35
LIMS1
MAP3K20
MAP3K7
MYO3A
MYOC
MYT1L
NAT8
NEK6
NEK8
NKIRAS1
NRP1
NUAK2
NUP37
OSR1
OTUB1
OXSR1
PAK1
PARD6A
PIK3R1
PIK3R2
PLEK
PLEKHB1
PLEKHJ1
PLK4
PML
POMK
PPP2R2A
PPP3CC
PPP6C
PREB
PREX2
PRPF4
PSMD14
RAB13
RAB25
RAB33B
RAB34
RAB38
RAB3B
RAB6B
RAN
RAP2A
RASD2
RASL12
RGS19
RHEBL1
RHOA
RHOD
RHOG
RHOH
RHOJ
RHPN2
RNF130
RNF146
RNF5
RPAP3
RPS27A
RRH
RTKN
SAMD8
SAT2
SKAP2
SKI
SMAD1
SMAD2
SMAD3
SMAD4
SMAD6
SMAD7
SMURF2
SNTG1
SNX6
SOCS6
SQSTM1
STK35
STRAP
STUB1
STX8
STYXL1
TGFB1
TGFB2
TGFB3
TGFBR2
TGFBRAP1
TNNT1
TRAF6
TRAP1
TSC22D1
TSSK1B
TSSK4
TTC1
TTC27
TTPAL
UBA52
UBB
UBD
UBE2E3
UBE2Z
UBXN1
USP2
USP45
VEPH1
WDR13
WDR33
WDR61
XIAP
ZFYVE9
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Entrez ID |
3702 |
7046 |
HPRD ID |
01746 |
01822 |
Ensembl ID |
ENSG00000113263
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ENSG00000106799
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Uniprot IDs |
Q08881
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B4DXN7
B4DY26
P36897
Q5T7S2
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PDB IDs |
1SM2
1SNU
1SNX
2E6I
2LMJ
2YUQ
3MIY
3MJ1
3MJ2
3QGW
3QGY
3T9T
3V5J
3V5L
3V8T
3V8W
4HCT
4HCU
4HCV
4KIO
4L7S
4M0Y
4M0Z
4M12
4M13
4M14
4M15
4MF0
4MF1
4PP9
4PPA
4PPB
4PPC
4PQN
4QD6
4RFM
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1B6C
1IAS
1PY5
1RW8
1TBI
1VJY
2L5S
2PJY
2WOT
2WOU
2X7O
3FAA
3GXL
3HMM
3KCF
3KFD
3TZM
4X0M
4X2F
4X2G
4X2J
4X2K
4X2N
5E8S
5E8T
5E8U
5E8W
5E8X
5E8Z
5E90
5FRI
5QIK
5QIL
5QIM
5QTZ
5QU0
5USQ
6B8Y
6MAC
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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