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AQP6 and GRM2
Data Source:
BioGRID
(two hybrid)
AQP6
GRM2
Description
aquaporin 6
glutamate metabotropic receptor 2
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Apical Plasma Membrane
Cytoplasmic Vesicle Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Axon
Dendrite
Presynaptic Membrane
Astrocyte Projection
Integral Component Of Postsynaptic Membrane
Molecular Function
Protein Binding
Nitrate Transmembrane Transporter Activity
Water Channel Activity
Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity
Group II Metabotropic Glutamate Receptor Activity
G Protein-coupled Receptor Activity
Calcium Channel Regulator Activity
Protein Binding
Glutamate Receptor Activity
Scaffold Protein Binding
Biological Process
Water Transport
Excretion
Carbon Dioxide Transport
Nitrate Transport
Odontogenesis
Transmembrane Transport
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway
G Protein-coupled Glutamate Receptor Signaling Pathway
Chemical Synaptic Transmission
Gene Expression
Glutamate Secretion
Regulation Of Protein Kinase B Signaling
Regulation Of Synaptic Transmission, Glutamatergic
Glutamate Homeostasis
Pathways
Passive transport by Aquaporins
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
LY2140023
Diseases
GWAS
Interacting Genes
304 interacting genes:
ABCG1
ABHD16A
ACSL5
ADGRE2
ADIPOQ
AGMO
AGPAT3
AGPAT4
AGTRAP
AIG1
ALOX5AP
ANKRD46
AOC2
APOA2
AQP1
ARL6IP1
ARL6IP6
ARV1
ATP13A1
ATP6V0C
BET1
BMP10
BRICD5
BSG
BTN2A2
C14orf180
C2CD2L
C3orf52
C4orf3
C5
C5orf46
CCDC167
CCL22
CCL4L2
CD52
CD68
CD81
CDIPT
CGREF1
CLDN19
CLDN4
CLDND2
CMTM3
CMTM5
CMTM7
CNIH1
CNIH3
CORIN
COX20
CTSA
CTXN3
CXCL16
CXCL9
CXorf66
CYB561
CYB561A3
CYB561D1
CYB5B
CYB5R3
CYBC1
CYP4F2
CYP4F22
DEFB103A
DEFB103B
DEFB108B
DEFB127
DERL1
DGAT2L6
DHRSX
DNAJC30
EBP
EFNA5
EMC6
EMP1
EMP3
ERG28
ERMP1
FA2H
FAM177A1
FAXDC2
FDFT1
FUNDC2
FXYD3
FXYD6
FXYD6-FXYD2
GAST
GIMAP1
GIMAP5
GJB2
GKN1
GOLT1A
GOSR2
GPR151
GPR152
GPR25
GRM2
GYPC
HMOX1
HMOX2
HSD3B1
HTATIP2
ICMT
IFITM3
IFNGR1
IGFBP5
INSIG1
INSIG2
ITGAM
JAGN1
JPH1
KCNK1
LEMD1
LEPROT
LHFPL5
LNPEP
LPAR3
LSS
LY6D
MAL
MAL2
MALL
MARCHF2
MARCHF5
MFF
MFSD3
MFSD5
MGAM
MGLL
MMP14
MS4A1
MS4A13
MYADML2
NEU1
NINJ1
NINJ2
NKG7
NRM
ORMDL1
ORMDL2
ORMDL3
OTULINL
PAEP
PDZK1IP1
PEDS1-UBE2V1
PEMT
PEX11G
PEX16
PIGF
PLLP
PLP1
PLPP6
PRAF2
PRB1
PRH1
PRRT2
PTPN1
PTPN9
RAB18
RFT1
RHD
RPRM
RTP2
RUSF1
SACM1L
SCAMP4
SCAMP5
SCD
SCGB1A1
SEC22A
SEC22B
SEC61G
SELENOK
SERF1A
SERF1B
SERP1
SERP2
SFRP4
SFT2D1
SFT2D2
SFXN1
SFXN2
SFXN3
SFXN5
SLC16A12
SLC16A13
SLC25A46
SLC30A2
SLC30A8
SLC35A1
SLC35B1
SLC35B2
SLC35B4
SLC35E4
SLC35F1
SLC35F6
SLC35G2
SLC38A1
SLC39A2
SLC39A7
SLC39A9
SLC41A1
SLC41A2
SLC52A1
SLC66A1
SLC66A2
SLC7A1
SLC7A8
SLCO3A1
SMAGP
SMCO4
SMIM1
SNORC
ST6GAL2
STARD3
STATH
STRIT1
STX12
STX1B
STX3
STX5
STX6
STX7
SYNDIG1
SYNGR1
SYNJ2BP
TAP1
TBC1D20
TFRC
THBD
THSD7A
THSD7B
TIMM23
TLCD1
TMEM100
TMEM107
TMEM115
TMEM119
TMEM120A
TMEM120B
TMEM128
TMEM140
TMEM143
TMEM144
TMEM14A
TMEM167B
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM229B
TMEM234
TMEM239
TMEM242
TMEM243
TMEM254
TMEM262
TMEM42
TMEM50A
TMEM51
TMEM60
TMEM65
TMEM69
TMEM74
TMEM86B
TMEM97
TMIE
TMUB2
TMX2
TNFRSF10C
TOMM22
TOMM6
TPRG1
TREX1
TSPO2
UBE2J2
UBTD2
UBXN8
UNC50
UNC93A
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAPA
VAPB
VEZT
VKORC1L1
VMA21
VRK2
VSTM1
VTI1B
WFS1
XKR3
YIF1A
YIPF1
YIPF2
YIPF4
YIPF6
ZDHHC21
ZDHHC24
ZNF587
29 interacting genes:
ACBD5
AQP6
BIK
CCDC107
CLDN2
CLDN9
CPLX4
CYB5R3
GNA15
GNAQ
GRIP1
LMNA
MFSD14B
MGST3
MMGT1
NAALADL2
PDZK1IP1
RGS12
SAR1A
SDCBP
SLC30A8
SLC38A1
STOM
TAMALIN
TMEM130
TMEM237
TMEM248
TSPAN18
UBQLN1
Entrez ID
363
2912
HPRD ID
03226
04977
Ensembl ID
ENSG00000086159
ENSG00000164082
Uniprot IDs
Q13520
Q14416
PDB IDs
1S6E
4XAQ
4XAS
5CNI
5CNJ
5KZN
5KZQ
Enriched GO Terms of Interacting Partners
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