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AQP6 and APOA2
Data Source:
BioGRID
(two hybrid)
AQP6
APOA2
Description
aquaporin 6
apolipoprotein A2
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Apical Plasma Membrane
Cytoplasmic Vesicle Membrane
Extracellular Region
Early Endosome
Endoplasmic Reticulum Lumen
Cytosol
Very-low-density Lipoprotein Particle
High-density Lipoprotein Particle
Spherical High-density Lipoprotein Particle
Chylomicron
Extracellular Exosome
Blood Microparticle
Molecular Function
Protein Binding
Nitrate Transmembrane Transporter Activity
Water Channel Activity
Signaling Receptor Binding
Lipid Transporter Activity
Protein Binding
Phospholipid Binding
High-density Lipoprotein Particle Binding
Lipid Binding
Cholesterol Binding
Heat Shock Protein Binding
Phosphatidylcholine Binding
Apolipoprotein Receptor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Lipase Inhibitor Activity
Phosphatidylcholine-sterol O-acyltransferase Activator Activity
High-density Lipoprotein Particle Receptor Binding
Cholesterol Transfer Activity
Biological Process
Water Transport
Excretion
Carbon Dioxide Transport
Nitrate Transport
Odontogenesis
Transmembrane Transport
Retinoid Metabolic Process
Negative Regulation Of Cytokine Production Involved In Immune Response
Triglyceride Metabolic Process
Phosphatidylcholine Biosynthetic Process
Cholesterol Metabolic Process
Phospholipid Catabolic Process
Response To Glucose
Positive Regulation Of Cholesterol Esterification
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Viral Process
Protein Oxidation
Peptidyl-methionine Modification
Regulation Of Lipid Metabolic Process
Cholesterol Transport
Regulation Of Protein Stability
Negative Regulation Of Cholesterol Transport
Positive Regulation Of Interleukin-8 Production
Cholesterol Efflux
Phospholipid Efflux
Triglyceride-rich Lipoprotein Particle Remodeling
Chylomicron Remodeling
Low-density Lipoprotein Particle Remodeling
High-density Lipoprotein Particle Remodeling
Chylomicron Assembly
High-density Lipoprotein Particle Assembly
High-density Lipoprotein Particle Clearance
Lipoprotein Metabolic Process
Cholesterol Homeostasis
Post-translational Protein Modification
Reverse Cholesterol Transport
Cellular Protein Metabolic Process
Diacylglycerol Catabolic Process
Positive Regulation Of Phagocytosis
Protein Stabilization
Negative Regulation Of Lipid Catabolic Process
Positive Regulation Of Lipid Catabolic Process
Negative Regulation Of Lipase Activity
Negative Regulation Of Cholesterol Import
Negative Regulation Of Cholesterol Transporter Activity
Intermembrane Lipid Transfer
Pathways
Passive transport by Aquaporins
PPARA activates gene expression
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron assembly
Chylomicron remodeling
Retinoid metabolism and transport
Retinoid metabolism and transport
Drugs
Zinc
Copper
Zinc acetate
Diseases
Familial amyloidosis
GWAS
Interacting Genes
304 interacting genes:
ABCG1
ABHD16A
ACSL5
ADGRE2
ADIPOQ
AGMO
AGPAT3
AGPAT4
AGTRAP
AIG1
ALOX5AP
ANKRD46
AOC2
APOA2
AQP1
ARL6IP1
ARL6IP6
ARV1
ATP13A1
ATP6V0C
BET1
BMP10
BRICD5
BSG
BTN2A2
C14orf180
C2CD2L
C3orf52
C4orf3
C5
C5orf46
CCDC167
CCL22
CCL4L2
CD52
CD68
CD81
CDIPT
CGREF1
CLDN19
CLDN4
CLDND2
CMTM3
CMTM5
CMTM7
CNIH1
CNIH3
CORIN
COX20
CTSA
CTXN3
CXCL16
CXCL9
CXorf66
CYB561
CYB561A3
CYB561D1
CYB5B
CYB5R3
CYBC1
CYP4F2
CYP4F22
DEFB103A
DEFB103B
DEFB108B
DEFB127
DERL1
DGAT2L6
DHRSX
DNAJC30
EBP
EFNA5
EMC6
EMP1
EMP3
ERG28
ERMP1
FA2H
FAM177A1
FAXDC2
FDFT1
FUNDC2
FXYD3
FXYD6
FXYD6-FXYD2
GAST
GIMAP1
GIMAP5
GJB2
GKN1
GOLT1A
GOSR2
GPR151
GPR152
GPR25
GRM2
GYPC
HMOX1
HMOX2
HSD3B1
HTATIP2
ICMT
IFITM3
IFNGR1
IGFBP5
INSIG1
INSIG2
ITGAM
JAGN1
JPH1
KCNK1
LEMD1
LEPROT
LHFPL5
LNPEP
LPAR3
LSS
LY6D
MAL
MAL2
MALL
MARCHF2
MARCHF5
MFF
MFSD3
MFSD5
MGAM
MGLL
MMP14
MS4A1
MS4A13
MYADML2
NEU1
NINJ1
NINJ2
NKG7
NRM
ORMDL1
ORMDL2
ORMDL3
OTULINL
PAEP
PDZK1IP1
PEDS1-UBE2V1
PEMT
PEX11G
PEX16
PIGF
PLLP
PLP1
PLPP6
PRAF2
PRB1
PRH1
PRRT2
PTPN1
PTPN9
RAB18
RFT1
RHD
RPRM
RTP2
RUSF1
SACM1L
SCAMP4
SCAMP5
SCD
SCGB1A1
SEC22A
SEC22B
SEC61G
SELENOK
SERF1A
SERF1B
SERP1
SERP2
SFRP4
SFT2D1
SFT2D2
SFXN1
SFXN2
SFXN3
SFXN5
SLC16A12
SLC16A13
SLC25A46
SLC30A2
SLC30A8
SLC35A1
SLC35B1
SLC35B2
SLC35B4
SLC35E4
SLC35F1
SLC35F6
SLC35G2
SLC38A1
SLC39A2
SLC39A7
SLC39A9
SLC41A1
SLC41A2
SLC52A1
SLC66A1
SLC66A2
SLC7A1
SLC7A8
SLCO3A1
SMAGP
SMCO4
SMIM1
SNORC
ST6GAL2
STARD3
STATH
STRIT1
STX12
STX1B
STX3
STX5
STX6
STX7
SYNDIG1
SYNGR1
SYNJ2BP
TAP1
TBC1D20
TFRC
THBD
THSD7A
THSD7B
TIMM23
TLCD1
TMEM100
TMEM107
TMEM115
TMEM119
TMEM120A
TMEM120B
TMEM128
TMEM140
TMEM143
TMEM144
TMEM14A
TMEM167B
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM229B
TMEM234
TMEM239
TMEM242
TMEM243
TMEM254
TMEM262
TMEM42
TMEM50A
TMEM51
TMEM60
TMEM65
TMEM69
TMEM74
TMEM86B
TMEM97
TMIE
TMUB2
TMX2
TNFRSF10C
TOMM22
TOMM6
TPRG1
TREX1
TSPO2
UBE2J2
UBTD2
UBXN8
UNC50
UNC93A
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAMP5
VAPA
VAPB
VEZT
VKORC1L1
VMA21
VRK2
VSTM1
VTI1B
WFS1
XKR3
YIF1A
YIPF1
YIPF2
YIPF4
YIPF6
ZDHHC21
ZDHHC24
ZNF587
31 interacting genes:
ABCA13
APOA1
APOC1
APOD
APOF
AQP6
C4A
CATSPER1
CIAO2A
CREB3
CYBC1
GET1
GJA8
HSD17B13
KIR2DL3
LMNA
MUC1
NAXE
NDRG1
PANX1
PDZK1IP1
PLTP
PSCA
SCARB1
SLC7A1
SSMEM1
STOM
TMEM45A
TMEM82
TREM2
VKORC1
Entrez ID
363
336
HPRD ID
03226
00129
Ensembl ID
ENSG00000086159
ENSG00000158874
Uniprot IDs
Q13520
P02652
PDB IDs
1S6E
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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