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GRM2 and STOM
Data Source:
BioGRID
(two hybrid)
GRM2
STOM
Description
glutamate metabotropic receptor 2
stomatin
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Axon
Dendrite
Presynaptic Membrane
Astrocyte Projection
Integral Component Of Postsynaptic Membrane
Extracellular Space
Mitochondrion
Endoplasmic Reticulum
Cytoskeleton
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Vesicle
Azurophil Granule Membrane
Specific Granule Membrane
Melanosome
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Tertiary Granule Membrane
Blood Microparticle
Molecular Function
Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity
Group II Metabotropic Glutamate Receptor Activity
G Protein-coupled Receptor Activity
Calcium Channel Regulator Activity
Protein Binding
Glutamate Receptor Activity
Scaffold Protein Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
RNA Polymerase Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway
G Protein-coupled Glutamate Receptor Signaling Pathway
Chemical Synaptic Transmission
Gene Expression
Glutamate Secretion
Regulation Of Protein Kinase B Signaling
Regulation Of Synaptic Transmission, Glutamatergic
Glutamate Homeostasis
Neutrophil Degranulation
Positive Regulation By Host Of Viral Genome Replication
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Acid-sensing Ion Channel Activity
Pathways
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Stimuli-sensing channels
Neutrophil degranulation
Drugs
LY2140023
Diseases
Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS
Interacting Genes
29 interacting genes:
ACBD5
AQP6
BIK
CCDC107
CLDN2
CLDN9
CPLX4
CYB5R3
GNA15
GNAQ
GRIP1
LMNA
MFSD14B
MGST3
MMGT1
NAALADL2
PDZK1IP1
RGS12
SAR1A
SDCBP
SLC30A8
SLC38A1
STOM
TAMALIN
TMEM130
TMEM237
TMEM248
TSPAN18
UBQLN1
81 interacting genes:
AIG1
APOA2
ASIC1
ASIC2
ASIC3
ATP1B3
ATP6V0B
ATP6V0C
BCL2L2
BNIP1
C2
C3orf52
CFHR5
CHST1
CLDN19
CLRN2
CMTM5
CNIH3
CTXN3
CYB5B
CYB5R3
DAGLA
DVL3
EMP1
ERG28
FAXDC2
FUNDC2
GIMAP1
GIMAP5
GPR25
GPR37L1
GRM2
HMOX2
KCNK1
KTN1
LANCL1
LNPEP
MGLL
MMP14
NKG7
ORMDL1
PEDS1-UBE2V1
PEMT
PGA4
PMP22
PTCH1
RPL13A
RPRM
RTP2
RUVBL1
RUVBL2
SCD
SELENOK
SERP2
SFT2D1
SFT2D2
SFXN1
SFXN5
SLC2A1
SLC35B4
SMCO4
STX6
TECR
THSD7B
TMEM109
TMEM120B
TMEM140
TMEM14B
TMEM203
TMEM208
TMEM254
TMEM60
TMEM86B
TMEM98
TMPO
TNF
TNFRSF10C
TSPO2
VAMP4
WFDC2
YIPF6
Entrez ID
2912
2040
HPRD ID
04977
00585
Ensembl ID
ENSG00000164082
ENSG00000148175
Uniprot IDs
Q14416
A0A024R882
F8VSL7
P27105
PDB IDs
4XAQ
4XAS
5CNI
5CNJ
5KZN
5KZQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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