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RBBP4 and H3C14
Data Source:
HPRD
(in vitro)
RBBP4
H3C14
Description
RB binding protein 4, chromatin remodeling factor
H3 clustered histone 14
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Sin3 Complex
NuRD Complex
NURF Complex
Protein-containing Complex
CAF-1 Complex
ESC/E(Z) Complex
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Protein Binding
DNA-dependent ATPase Activity
Nucleosomal DNA Binding
Histone Binding
Histone Deacetylase Binding
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Biological Process
DNA Replication
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Chromatin Remodeling
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Chromatin Assembly
CENP-A Containing Nucleosome Assembly
ATP-dependent Chromatin Remodeling
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Cell Cycle
Response To Growth Hormone
Negative Regulation Of G0 To G1 Transition
Regulation Of Signal Transduction By P53 Class Mediator
RDNA Heterochromatin Assembly
Chromatin Organization
Nucleosome Assembly
Blood Coagulation
Interleukin-7-mediated Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing By MiRNA
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
Cyclin A:Cdk2-associated events at S phase entry
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Amyloid fiber formation
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Interacting Genes
64 interacting genes:
AEBP2
ANXA7
ARMC12
BCL11A
BCL11B
BRCA1
BRMS1
BRMS1L
CDKN1A
CHAF1B
CREB1
CREBBP
CYTOR
DHX30
ERCC6
ESR1
FOXK2
H1-1
H2AC20
H3-4
H3C1
H3C14
H4-16
H4C14
HAT1
HDAC1
HDAC2
HDAC3
HDAC4
HMOX2
ING1
KPNA3
KPNA5
LIN37
LIN52
LIN9
LMNA
MBD2
MBD3
MBD3L2
MTA1
MTA2
MYBL2
NR2E3
PRDM16
RB1
RBBP7
RBP1
RPN1
RPN2
RYBP
SALL4
SAP30
SIN3A
SMN1
SP1
SP3
SPEN
STAT5B
SUMO2
SUV39H1
TK1
TSSK3
XRCC6
60 interacting genes:
ARID4A
ATRX
AURKB
BIRC5
BRD1
BRD4
BRD7
BRPF1
CDCA8
CDK8
CHUK
DDB2
DNMT3L
EHMT2
ELP3
EP300
HDGFL2
INCENP
ING1
JADE1
KAT2A
KAT2B
KAT5
KAT6A
KDM1A
KDM2A
KDM3A
KDM4C
KDM6A
KMT2A
KMT2B
KMT2C
KMT2D
MSL2
NAP1L4
NASP
NCOA6
NRDC
NSD2
PHF21A
PIM1
PKN1
PRMT6
PTMA
PWWP3A
RBBP4
RBBP5
RERE
RNF20
RNF4
RPS6KA5
SETD1A
SETD1B
SETD7
SMARCA4
SMYD2
STAT6
TBL1X
UHRF1
VRK1
Entrez ID
5928
126961
HPRD ID
04232
11822
Ensembl ID
ENSG00000162521
ENSG00000203811
Uniprot IDs
Q09028
Q71DI3
PDB IDs
2XU7
3GFC
4PBY
4PBZ
4PC0
4R7A
5FXY
5VTB
5WAI
5WAK
5XWR
5XXQ
5Y1U
6BW3
6BW4
6C23
6C24
6G16
6NQ3
6ZRC
2IIJ
2X4W
2X4X
2X4Y
3AV1
3DB3
3MO8
3QO2
3R93
4MZF
4MZG
4MZH
4OUC
5B0Y
5B0Z
5B40
5BO0
5CIU
5VAC
6ACE
6FML
6T79
6T7A
6T7B
6T7C
6T7D
6X59
6X5A
6XJD
6Y5D
6Y5E
7BQZ
7BU9
7JO9
7JOA
Enriched GO Terms of Interacting Partners
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