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RBBP4 and SALL4
Data Source:
BioGRID
(pull down)
RBBP4
SALL4
Description
RB binding protein 4, chromatin remodeling factor
spalt like transcription factor 4
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Sin3 Complex
NuRD Complex
NURF Complex
Protein-containing Complex
CAF-1 Complex
ESC/E(Z) Complex
Heterochromatin
Nucleus
Nucleoplasm
Cytoplasm
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Protein Binding
DNA-dependent ATPase Activity
Nucleosomal DNA Binding
Histone Binding
Histone Deacetylase Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Transcription Factor Binding
Metal Ion Binding
Biological Process
DNA Replication
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Chromatin Remodeling
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Chromatin Assembly
CENP-A Containing Nucleosome Assembly
ATP-dependent Chromatin Remodeling
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Cell Cycle
Response To Growth Hormone
Negative Regulation Of G0 To G1 Transition
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Transcription By RNA Polymerase II
Inner Cell Mass Cell Proliferation
Neural Tube Closure
Ventricular Septum Development
Regulation Of Transcription By RNA Polymerase II
Embryonic Limb Morphogenesis
Somatic Stem Cell Population Maintenance
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
Cyclin A:Cdk2-associated events at S phase entry
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Transcriptional regulation of pluripotent stem cells
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
Duane-radial ray syndrome and IVIC syndrome; Okihiro syndrome
GWAS
Male infertility (
19478329
)
Neuroblastoma (pediatric) (
32599975
)
Tourette's syndrome or obsessive-compulsive disorder (
25158072
)
Interacting Genes
64 interacting genes:
AEBP2
ANXA7
ARMC12
BCL11A
BCL11B
BRCA1
BRMS1
BRMS1L
CDKN1A
CHAF1B
CREB1
CREBBP
CYTOR
DHX30
ERCC6
ESR1
FOXK2
H1-1
H2AC20
H3-4
H3C1
H3C14
H4-16
H4C14
HAT1
HDAC1
HDAC2
HDAC3
HDAC4
HMOX2
ING1
KPNA3
KPNA5
LIN37
LIN52
LIN9
LMNA
MBD2
MBD3
MBD3L2
MTA1
MTA2
MYBL2
NR2E3
PRDM16
RB1
RBBP7
RBP1
RPN1
RPN2
RYBP
SALL4
SAP30
SIN3A
SMN1
SP1
SP3
SPEN
STAT5B
SUMO2
SUV39H1
TK1
TSSK3
XRCC6
2 interacting genes:
CRBN
RBBP4
Entrez ID
5928
57167
HPRD ID
04232
08458
Ensembl ID
ENSG00000162521
ENSG00000101115
Uniprot IDs
Q09028
Q9UJQ4
PDB IDs
2XU7
3GFC
4PBY
4PBZ
4PC0
4R7A
5FXY
5VTB
5WAI
5WAK
5XWR
5XXQ
5Y1U
6BW3
6BW4
6C23
6C24
6G16
6NQ3
6ZRC
5XWR
6UML
7BQU
7BQV
Enriched GO Terms of Interacting Partners
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