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IL3RA and PPP1CC
Data Source:
BioGRID
(two hybrid)
IL3RA
PPP1CC
Description
interleukin 3 receptor subunit alpha
protein phosphatase 1 catalytic subunit gamma
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Receptor Complex
Protein Phosphatase Type 1 Complex
Condensed Chromosome Kinetochore
Chromosome, Telomeric Region
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Focal Adhesion
Nuclear Speck
Midbody
Cleavage Furrow
Protein-containing Complex
Dendritic Spine
PTW/PP1 Phosphatase Complex
Presynapse
Glutamatergic Synapse
Molecular Function
Cytokine Receptor Activity
Interleukin-3 Receptor Activity
Protein Binding
Cytokine Binding
RNA Binding
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Lamin Binding
Protein C-terminus Binding
Protein Phosphatase 1 Binding
Phosphatase Activity
Protein Kinase Binding
Protein Domain Specific Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein N-terminus Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Biological Process
MAPK Cascade
Cytokine-mediated Signaling Pathway
Cellular Response To Interleukin-3
Interleukin-3-mediated Signaling Pathway
Glycogen Metabolic Process
Protein Dephosphorylation
Cell Cycle
Neuron Differentiation
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Nucleocytoplasmic Transport
Cell Division
Positive Regulation Of Glial Cell Proliferation
Pathways
Interleukin-3, Interleukin-5 and GM-CSF signaling
RAF/MAP kinase cascade
Interleukin receptor SHC signaling
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Triglyceride catabolism
Downregulation of TGF-beta receptor signaling
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Circadian Clock
RHO GTPases Activate Formins
RAF activation
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Signaling by MRAS-complex mutants
Drugs
Sargramostim
Tagraxofusp
9,10-Deepithio-9,10-Didehydroacanthifolicin
Calyculin A
Motuporin
Diseases
GWAS
Schizophrenia (
17522711
)
Heart rate (
23583979
)
Interacting Genes
32 interacting genes:
BMP10
C2CD2L
CDC25A
CDK1
CISH
CLDN19
CSF2
CSF2RB
EMP3
FOXP1
GIMAP1
GNA12
IL3
JAGN1
JAK1
JAK2
LNX1
NINJ2
NR0B2
PAQR5
PPP1CC
SAE1
SERP1
SGK2
SMAGP
SYS1
TMEM128
TMEM147
TMEM254
TMEM65
TRARG1
VAMP5
131 interacting genes:
AATK
ABT1
ACAD8
AKAP11
ANKRD42
APIP
APP
ASH2L
AURKA
B4GAT1
BMPR2
BTBD10
C14orf180
C1QA
C9orf50
CEP126
CLMN
CLOCK
CLTC
CNST
COPS5
CSNK1A1
CSNK1E
CSNK2B
CSRNP1
CSRNP2
CTSL
CYFIP1
DACT1
DEAF1
DELEC1
DYNLT4
DYRK4
EIF2AK2
ELP4
ENKD1
FBXW11
FTL
FXYD6
GLB1L
GOLGA7
GSTZ1
HCFC1
HDAC6
HMGN1
IFTAP
IL3RA
INSYN1
JAK2
KCTD20
KDM4D
KRCC1
LMTK2
MAP4K4
MAPT
MYO16
NAPEPLD
NEK2
NMT2
NONO
NRBP1
NUAK1
PHACTR4
PHC1
PIAS1
POLR1F
PPP1R11
PPP1R15B
PPP1R16A
PPP1R18
PPP1R2
PPP1R2B
PPP1R2C
PPP1R32
PPP1R35
PPP1R3A
PPP1R3B
PPP1R3C
PPP1R3D
PPP1R7
PPP1R8
PPP1R9A
PPP1R9B
PPP2R5C
PRR16
RAF1
RB1
RIF1
RNF19B
RORC
RPL7
RPRD2
RRM1
RRP1B
SDR39U1
SFRP1
SGCE
SH3RF2
SHANK3
SMARCB1
SMG6
SPATC1L
SPOCD1
STAM
STARD9
STAU1
SUMO2
TACC2
TBC1D19
TEFM
TEX36
TLX1
TLX3
TMEM120A
TNS1
TOPBP1
TOR1AIP1
TP53
TP53BP2
TPRN
TRA2A
VSTM4
WBP11
YLPM1
YWHAZ
ZDBF2
ZFYVE9
ZNF24
ZNF318
ZNF629
ZNF667
Entrez ID
3563
5501
HPRD ID
02392
08911
Ensembl ID
ENSG00000185291
ENSG00000186298
Uniprot IDs
P26951
A0A024RBP2
P36873
PDB IDs
4JZJ
5UV8
5UWC
6NMY
1IT6
1JK7
1U32
2BCD
2BDX
4UT2
4UT3
5INB
5J28
Enriched GO Terms of Interacting Partners
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