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PPP1CC and PPP1R9B
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, proximity labelling technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid)
PPP1CC
PPP1R9B
Description
protein phosphatase 1 catalytic subunit gamma
protein phosphatase 1 regulatory subunit 9B
Image
No pdb structure
GO Annotations
Cellular Component
Protein Phosphatase Type 1 Complex
Condensed Chromosome Kinetochore
Chromosome, Telomeric Region
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Focal Adhesion
Nuclear Speck
Midbody
Cleavage Furrow
Protein-containing Complex
Dendritic Spine
PTW/PP1 Phosphatase Complex
Presynapse
Glutamatergic Synapse
Protein Phosphatase Type 1 Complex
Nucleoplasm
Cytoplasm
Plasma Membrane
Adherens Junction
Postsynaptic Density
Actin Cytoskeleton
Lamellipodium
Filopodium
Dendrite
Growth Cone
Cortical Actin Cytoskeleton
Ruffle Membrane
Neuronal Cell Body
Dendritic Spine Neck
Dendritic Spine Head
Cytoplasmic Side Of Dendritic Spine Plasma Membrane
Molecular Function
RNA Binding
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Lamin Binding
Protein C-terminus Binding
Protein Phosphatase 1 Binding
Phosphatase Activity
Protein Kinase Binding
Protein Domain Specific Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein N-terminus Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Protein Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Protein C-terminus Binding
Protein Phosphatase 1 Binding
Kinase Binding
D2 Dopamine Receptor Binding
Ion Channel Binding
Actin Filament Binding
Biological Process
Glycogen Metabolic Process
Protein Dephosphorylation
Cell Cycle
Neuron Differentiation
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Nucleocytoplasmic Transport
Cell Division
Positive Regulation Of Glial Cell Proliferation
Regulation Of Cell Growth By Extracellular Stimulus
Regulation Of Protein Phosphorylation
Response To Amphetamine
Developmental Process Involved In Reproduction
Protein Phosphorylation
Actin Filament Organization
Cell Cycle Arrest
Regulation Of Exit From Mitosis
Aging
Learning
RNA Splicing
Dendrite Development
Cell Migration
Calcium-mediated Signaling
Hippocampus Development
Cerebral Cortex Development
Actin Filament Depolymerization
Negative Regulation Of Cell Growth
Neuron Projection Development
Negative Regulation Of Phosphoprotein Phosphatase Activity
Response To Prostaglandin E
Response To Nicotine
Cellular Response To Drug
Response To Immobilization Stress
Regulation Of Cell Population Proliferation
Filopodium Assembly
Response To Steroid Hormone
Modulation Of Chemical Synaptic Transmission
Male Mating Behavior
Reproductive System Development
Cellular Response To Morphine
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Estradiol Stimulus
Response To Clozapine
Cellular Response To Peptide
Positive Regulation Of Protein Localization To Plasma Membrane
Protein Localization To Actin Cytoskeleton
Positive Regulation Of Protein Localization To Actin Cortical Patch
Response To Kainic Acid
Response To L-phenylalanine Derivative
Protein Localization To Cell Periphery
Regulation Of Opioid Receptor Signaling Pathway
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Triglyceride catabolism
Downregulation of TGF-beta receptor signaling
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Circadian Clock
RHO GTPases Activate Formins
RAF activation
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Signaling by MRAS-complex mutants
Drugs
9,10-Deepithio-9,10-Didehydroacanthifolicin
Calyculin A
Motuporin
Diseases
GWAS
Heart rate (
23583979
)
Platelet distribution width (
32888494
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
131 interacting genes:
AATK
ABT1
ACAD8
AKAP11
ANKRD42
APIP
APP
ASH2L
AURKA
B4GAT1
BMPR2
BTBD10
C14orf180
C1QA
C9orf50
CEP126
CLMN
CLOCK
CLTC
CNST
COPS5
CSNK1A1
CSNK1E
CSNK2B
CSRNP1
CSRNP2
CTSL
CYFIP1
DACT1
DEAF1
DELEC1
DYNLT4
DYRK4
EIF2AK2
ELP4
ENKD1
FBXW11
FTL
FXYD6
GLB1L
GOLGA7
GSTZ1
HCFC1
HDAC6
HMGN1
IFTAP
IL3RA
INSYN1
JAK2
KCTD20
KDM4D
KRCC1
LMTK2
MAP4K4
MAPT
MYO16
NAPEPLD
NEK2
NMT2
NONO
NRBP1
NUAK1
PHACTR4
PHC1
PIAS1
POLR1F
PPP1R11
PPP1R15B
PPP1R16A
PPP1R18
PPP1R2
PPP1R2B
PPP1R2C
PPP1R32
PPP1R35
PPP1R3A
PPP1R3B
PPP1R3C
PPP1R3D
PPP1R7
PPP1R8
PPP1R9A
PPP1R9B
PPP2R5C
PRR16
RAF1
RB1
RIF1
RNF19B
RORC
RPL7
RPRD2
RRM1
RRP1B
SDR39U1
SFRP1
SGCE
SH3RF2
SHANK3
SMARCB1
SMG6
SPATC1L
SPOCD1
STAM
STARD9
STAU1
SUMO2
TACC2
TBC1D19
TEFM
TEX36
TLX1
TLX3
TMEM120A
TNS1
TOPBP1
TOR1AIP1
TP53
TP53BP2
TPRN
TRA2A
VSTM4
WBP11
YLPM1
YWHAZ
ZDBF2
ZFYVE9
ZNF24
ZNF318
ZNF629
ZNF667
25 interacting genes:
ACTA1
ACTN2
ADRA1A
ADRA1B
ADRA2A
ADRA2B
ADRA2C
CCKAR
CCKBR
CDKN2A
CHRM3
DCX
DRD2
LRRC7
MAPK1
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP1R9A
PRKACA
RGS2
RPS6KB1
TGOLN2
TIAM1
Entrez ID
5501
84687
HPRD ID
08911
04506
Ensembl ID
ENSG00000186298
ENSG00000108819
Uniprot IDs
A0A024RBP2
P36873
Q96SB3
PDB IDs
1IT6
1JK7
1U32
2BCD
2BDX
4UT2
4UT3
5INB
5J28
Enriched GO Terms of Interacting Partners
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