TOE1 and SRSF6

Data Source:
BioGRID (two hybrid)

		TOE1	SRSF6
Description		target of EGR1, exonuclease	serine and arginine rich splicing factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck	Nucleoplasm Nuclear Speck
	Molecular Function	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Keratinocyte Proliferation MRNA 3'-end Processing Response To Insulin Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Cell Death Regulation Of Wound Healing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Adult body size ( 32376654) Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)
Interacting Genes		25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83	16 interacting genes: APP CLK1 LUC7L LUC7L2 PPARGC1A RBM10 RNPS1 SF3B4 SREK1 SRPK1 SRPK2 SRSF4 TERF1 TERF2 TOE1 TRA2B
Entrez ID		114034	6431
HPRD ID		18212	09054
Ensembl ID		ENSG00000132773	ENSG00000124193
Uniprot IDs		Q96GM8	Q13247
PDB IDs		2FC6
Enriched GO Terms of Interacting Partners?
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