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HTR6 and CD160
Data Source:
BioGRID
(biochemical)
HTR6
CD160
Description
5-hydroxytryptamine receptor 6
CD160 molecule
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cilium
Dendrite
Synapse
Extracellular Region
Plasma Membrane
Anchored Component Of Plasma Membrane
Molecular Function
Histamine Receptor Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
Neurotransmitter Receptor Activity
Signaling Receptor Binding
Protein Binding
Kinase Binding
MHC Class I Protein Complex Binding
MHC Class I Receptor Activity
MHC Class Ib Receptor Activity
Activating MHC Class I Receptor Activity
Biological Process
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Chemical Synaptic Transmission
Cerebral Cortex Cell Migration
Positive Regulation Of TOR Signaling
G Protein-coupled Serotonin Receptor Signaling Pathway
Angiogenesis
Adaptive Immune Response
Mucosal Immune Response
Positive Regulation Of Natural Killer Cell Cytokine Production
Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell
Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Angiogenesis
T Cell Costimulation
Positive Regulation Of Interferon-gamma Production
Innate Immune Response
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Immune Response
Defense Response To Gram-negative Bacterium
Negative Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation
Negative Regulation Of Adaptive Immune Memory Response
Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways
Serotonin receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Ziprasidone
Amitriptyline
Olanzapine
Clozapine
Loxapine
Imipramine
Chlorpromazine
Haloperidol
Amoxapine
Paroxetine
Cyclobenzaprine
Ergoloid mesylate
Doxepin
Quetiapine
Aripiprazole
Chlorprothixene
Dimethyltryptamine
Lysergic acid diethylamide
Iloperidone
SGS518
PRX-07034
SUVN-502
Sertindole
Mianserin
Asenapine
Zotepine
Setiptiline
Dihydroergocornine
Gilteritinib
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Chronotype (
26955885
27494321
)
Morning person (
30696823
)
Morning vs. evening chronotype (
26955885
27494321
)
Diastolic blood pressure (
30224653
)
Interacting Genes
31 interacting genes:
ABCA2
ACTB
AIP
AKR1A1
AP2M1
AP4S1
ATXN10
CHN1
CMSS1
COPS5
DDRGK1
DHRS1
EIF4A3
FYN
GNAQ
GNAS
HDGFL2
IDS
MAP1B
NF1
NRXN3
PARP8
RUNDC3A
SCHIP1
SLC6A1
SRRT
SYT5
THY1
TMEM98
TTYH1
UQCRFS1
8 interacting genes:
AGTRAP
CMTM5
CMTM6
MAL2
MDM4
SYP
THRA
TNFRSF14
Entrez ID
3362
11126
HPRD ID
03066
06833
Ensembl ID
ENSG00000158748
ENSG00000117281
Uniprot IDs
P50406
O95971
Q6FH89
PDB IDs
6NG3
6NG9
6NGG
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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