HOXA9 and MEIS2

Data Source:
HPRD (in vitro)

		HOXA9	MEIS2
Description		homeobox A9	Meis homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Chromatin Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Endothelial Cell Activation Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Uterus Development Definitive Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Hypertension ( 30487518) Mean arterial pressure ( 30487518) Mean corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		16 interacting genes: CREBBP CUL4A JUN KRTAP10-1 KRTAP9-3 MEIS1 MEIS2 NFKBIA PBX1 PBX2 PBX3 PLSCR1 RBPMS SMAD2 SMAD4 TRIP6	49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3
Entrez ID		3205	4212
HPRD ID		00844	03443
Ensembl ID		ENSG00000078399	ENSG00000134138
Uniprot IDs		P31269	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs			3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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