EHD2 and AP1M1

Data Source:
HPRD (in vitro)

		EHD2	AP1M1
Description		EH domain containing 2	adaptor related protein complex 1 subunit mu 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Microtubule Cytoskeleton Extrinsic Component Of Membrane Endocytic Vesicle Intracellular Membrane-bounded Organelle Intercellular Bridge Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Identical Protein Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Endocytosis Blood Coagulation Endosomal Transport Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Intracellular Protein Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus
Pathways		Factors involved in megakaryocyte development and platelet production	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS			Coronary artery disease ( 33020668)
Interacting Genes		14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	103 interacting genes: AMOT AP1M2 AP2B1 ARFRP1 ARL6IP4 ARNT2 ATF4 AXIN2 BACH2 BCAR3 BRCA1 C7orf57 CASP8 CCDC33 CEP57L1 CORO7 CTLA4 DCX DISC1 DVL2 DZIP3 EFEMP2 EHD2 ENTR1 ETV6 EVI5L FAM219B FAM9B FKBP7 FXR1 FXR2 GAK GCSAM GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KIF24 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 LAMP1 LDOC1 LNX1 LRATD2 LRMDA LZTS1 LZTS2 MDK MEA1 MID2 MTF1 MYOD1 NECAB1 NKAP NKAPD1 OLIG3 PAX6 PHC2 PICK1 PIGR PNMA5 PURB RAPGEF3 RNF19B ROPN1 RP9 RSPH14 RUNDC3A SDCBP2 SELP SLC2A4 SP4 SPATA6 SRPK2 SSX2IP TEPSIN TFIP11 TGOLN2 THAP6 TIFA TNIP1 TRIM27 TRIM41 VAMP4 VANGL2 ZBTB14 ZBTB3 ZBTB43 ZBTB44 ZBTB8A ZCCHC17 ZNF19 ZNF219 ZNF276 ZNF552 ZNF655 ZNF8 ZRANB1 ZSCAN16
Entrez ID		30846	8907
HPRD ID		10434	04639
Ensembl ID		ENSG00000024422	ENSG00000072958
Uniprot IDs		A0A024R0S6 Q9NZN4	A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?
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