AP1M1 and RNF19B

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		AP1M1	RNF19B
Description		adaptor related protein complex 1 subunit mu 1	ring finger protein 19B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Cytolytic Granule
	Molecular Function	Protein Binding Clathrin Adaptor Activity	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus	Protein Polyubiquitination Adaptive Immune Response Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Natural Killer Cell Mediated Cytotoxicity Protein Autoubiquitination
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		103 interacting genes: AMOT AP1M2 AP2B1 ARFRP1 ARL6IP4 ARNT2 ATF4 AXIN2 BACH2 BCAR3 BRCA1 C7orf57 CASP8 CCDC33 CEP57L1 CORO7 CTLA4 DCX DISC1 DVL2 DZIP3 EFEMP2 EHD2 ENTR1 ETV6 EVI5L FAM219B FAM9B FKBP7 FXR1 FXR2 GAK GCSAM GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KIF24 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 LAMP1 LDOC1 LNX1 LRATD2 LRMDA LZTS1 LZTS2 MDK MEA1 MID2 MTF1 MYOD1 NECAB1 NKAP NKAPD1 OLIG3 PAX6 PHC2 PICK1 PIGR PNMA5 PURB RAPGEF3 RNF19B ROPN1 RP9 RSPH14 RUNDC3A SDCBP2 SELP SLC2A4 SP4 SPATA6 SRPK2 SSX2IP TEPSIN TFIP11 TGOLN2 THAP6 TIFA TNIP1 TRIM27 TRIM41 VAMP4 VANGL2 ZBTB14 ZBTB3 ZBTB43 ZBTB44 ZBTB8A ZCCHC17 ZNF19 ZNF219 ZNF276 ZNF552 ZNF655 ZNF8 ZRANB1 ZSCAN16	31 interacting genes: AP1M1 APOL3 ASGR1 CDIPT CLEC1A DHODH FDPS GIMAP5 GOSR2 ICMT MEST MFSD5 MS4A1 NIPAL4 PPP1CC RAP1GDS1 SACM1L SEC22A SEC23A SELENOK SLC30A3 TAP1 TMEM100 TMEM120B TMEM208 TMEM31 TNF TSPAN2 UBE2D2 UBE2D3 UBE2L3
Entrez ID		8907	127544
HPRD ID		04639	13725
Ensembl ID		ENSG00000072958	ENSG00000116514
Uniprot IDs		A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5	Q6ZMZ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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