EHD2 and AP1M2

Data Source:
BioGRID (pull down)

		EHD2	AP1M2
Description		EH domain containing 2	adaptor related protein complex 1 subunit mu 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Microtubule Cytoskeleton Extrinsic Component Of Membrane Endocytic Vesicle Intracellular Membrane-bounded Organelle Intercellular Bridge Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Identical Protein Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Endocytosis Blood Coagulation Endosomal Transport Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Protein Targeting Vesicle Targeting Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Factors involved in megakaryocyte development and platelet production	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		30846	10053
HPRD ID		10434	06296
Ensembl ID		ENSG00000024422	ENSG00000129354
Uniprot IDs		A0A024R0S6 Q9NZN4	Q53GI5 Q9Y6Q5
PDB IDs
Enriched GO Terms of Interacting Partners?
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