AP1M1 and LAMP1

Data Source:
HPRD (in vitro, two hybrid)

		AP1M1	LAMP1
Description		adaptor related protein complex 1 subunit mu 1	lysosomal associated membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Plasma Membrane Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Autophagosome Membrane Cytoplasm Lysosome Lysosomal Membrane Late Endosome Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Late Endosome Membrane Azurophil Granule Membrane Sarcolemma Melanosome Neuronal Cell Body Cytolytic Granule Autolysosome Perinuclear Region Of Cytoplasm Phagolysosome Membrane Extracellular Exosome Alveolar Lamellar Body Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Clathrin Adaptor Activity	Virus Receptor Activity Protein Binding Enzyme Binding Protein Domain Specific Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Neutrophil Degranulation Regulation Of Defense Response To Virus By Virus	Neutrophil Degranulation Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Autophagic Cell Death Protein Stabilization Establishment Of Protein Localization To Organelle Golgi To Lysosome Transport Granzyme-mediated Programmed Cell Death Signaling Pathway Regulation Of Organelle Transport Along Microtubule
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Neutrophil degranulation
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668)	Bipolar disorder ( 31043756)
Interacting Genes		103 interacting genes: AMOT AP1M2 AP2B1 ARFRP1 ARL6IP4 ARNT2 ATF4 AXIN2 BACH2 BCAR3 BRCA1 C7orf57 CASP8 CCDC33 CEP57L1 CORO7 CTLA4 DCX DISC1 DVL2 DZIP3 EFEMP2 EHD2 ENTR1 ETV6 EVI5L FAM219B FAM9B FKBP7 FXR1 FXR2 GAK GCSAM GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KIF24 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 LAMP1 LDOC1 LNX1 LRATD2 LRMDA LZTS1 LZTS2 MDK MEA1 MID2 MTF1 MYOD1 NECAB1 NKAP NKAPD1 OLIG3 PAX6 PHC2 PICK1 PIGR PNMA5 PURB RAPGEF3 RNF19B ROPN1 RP9 RSPH14 RUNDC3A SDCBP2 SELP SLC2A4 SP4 SPATA6 SRPK2 SSX2IP TEPSIN TFIP11 TGOLN2 THAP6 TIFA TNIP1 TRIM27 TRIM41 VAMP4 VANGL2 ZBTB14 ZBTB3 ZBTB43 ZBTB44 ZBTB8A ZCCHC17 ZNF19 ZNF219 ZNF276 ZNF552 ZNF655 ZNF8 ZRANB1 ZSCAN16	4 interacting genes: AP1M1 AP2M1 SLC48A1 VSTM1
Entrez ID		8907	3916
HPRD ID		04639	01076
Ensembl ID		ENSG00000072958	ENSG00000185896
Uniprot IDs		A0A024R7K8 B3KNH5 Q59EK3 Q9BXS5	A0A024RDY3 P11279
PDB IDs
Enriched GO Terms of Interacting Partners?
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