EHD2 and EHBP1

Data Source:
HPRD (in vitro, in vivo)

		EHD2	EHBP1
Description		EH domain containing 2	EH domain binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Microtubule Cytoskeleton Extrinsic Component Of Membrane Endocytic Vesicle Intracellular Membrane-bounded Organelle Intercellular Bridge Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Nucleoplasm Endosome Microtubule Organizing Center Cytosol Plasma Membrane Filamentous Actin
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Endocytosis Blood Coagulation Endosomal Transport Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Endocytosis Protein Transport Actin Cytoskeleton Organization
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Body mass index ( 28892062 25673413) Coffee consumption ( 31046077) Coronary artery disease ( 29212778 33020668) Crohn's disease ( 22412388) Fruit consumption ( 32066663) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731) Prostate cancer ( 18264098 25939597 19767753) Regular attendance at a religious group ( 29970889) Total cholesterol levels ( 29403010)
Interacting Genes		14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	3 interacting genes: EHD1 EHD2 PACSIN1
Entrez ID		30846	23301
HPRD ID		10434	10109
Ensembl ID		ENSG00000024422	ENSG00000115504
Uniprot IDs		A0A024R0S6 Q9NZN4	A0A140VK17 A8K930 Q8NDI1
PDB IDs			2D89 6ZSH 6ZSI 6ZSJ
Enriched GO Terms of Interacting Partners?
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