GSC2 and DYRK1B

Data Source:
BioGRID (two hybrid)

		GSC2	DYRK1B
Description		goosecoid homeobox 2	dual specificity tyrosine phosphorylation regulated kinase 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis	Protein Phosphorylation Myoblast Fusion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Adipose Tissue Development
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Metabolite levels ( 22916037)	Macular thickness ( 30535121)
Interacting Genes		60 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587	12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP
Entrez ID		2928	9149
HPRD ID		03506	05188
Ensembl ID		ENSG00000063515	ENSG00000105204
Uniprot IDs		O15499	A0A024R0I0 A0A024R0J6 A0A024R0M8 Q9Y463
PDB IDs
Enriched GO Terms of Interacting Partners?
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