GSC2 and GUCA1A

Data Source:
BioGRID (two hybrid)

		GSC2	GUCA1A
Description		goosecoid homeobox 2	guanylate cyclase activator 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Photoreceptor Inner Segment Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis	Signal Transduction Visual Perception Phototransduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Calcium Ion
Pathways			Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristic acid
Diseases			Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Metabolite levels ( 22916037)	Spatial processing ( 31596458)
Interacting Genes		60 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587	9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B
Entrez ID		2928	2978
HPRD ID		03506	02648
Ensembl ID		ENSG00000063515	ENSG00000048545
Uniprot IDs		O15499	B2R9P6 P43080
PDB IDs
Enriched GO Terms of Interacting Partners?
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