DYRK1B and TROAP

Data Source:
BioGRID (two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, affinity chromatography technology)

		DYRK1B	TROAP
Description		dual specificity tyrosine phosphorylation regulated kinase 1B	trophinin associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Protein Phosphorylation Myoblast Fusion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Adipose Tissue Development	Cell Adhesion
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Macular thickness ( 30535121)
Interacting Genes		12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP	20 interacting genes: BANP BYSL C19orf54 DYNLT1 DYRK1A DYRK1B GIGYF1 KRT31 KRT40 KRT8 MAPRE1 MAPRE3 NBPF19 NOTCH2NLA OIP5 SSC4D TP53BP2 TRAF2 TRIM23 TRO
Entrez ID		9149	10024
HPRD ID		05188	04849
Ensembl ID		ENSG00000105204	ENSG00000135451
Uniprot IDs		A0A024R0I0 A0A024R0J6 A0A024R0M8 Q9Y463	F8W130 Q12815
PDB IDs
Enriched GO Terms of Interacting Partners?
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