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STOM and APOA2
Data Source:
BioGRID
(two hybrid)
STOM
APOA2
Description
stomatin
apolipoprotein A2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Mitochondrion
Endoplasmic Reticulum
Cytoskeleton
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Vesicle
Azurophil Granule Membrane
Specific Granule Membrane
Melanosome
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Tertiary Granule Membrane
Blood Microparticle
Extracellular Region
Early Endosome
Endoplasmic Reticulum Lumen
Cytosol
Very-low-density Lipoprotein Particle
High-density Lipoprotein Particle
Spherical High-density Lipoprotein Particle
Chylomicron
Extracellular Exosome
Blood Microparticle
Molecular Function
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
RNA Polymerase Binding
Signaling Receptor Binding
Lipid Transporter Activity
Protein Binding
Phospholipid Binding
High-density Lipoprotein Particle Binding
Lipid Binding
Cholesterol Binding
Heat Shock Protein Binding
Phosphatidylcholine Binding
Apolipoprotein Receptor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Lipase Inhibitor Activity
Phosphatidylcholine-sterol O-acyltransferase Activator Activity
High-density Lipoprotein Particle Receptor Binding
Cholesterol Transfer Activity
Biological Process
Neutrophil Degranulation
Positive Regulation By Host Of Viral Genome Replication
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Acid-sensing Ion Channel Activity
Retinoid Metabolic Process
Negative Regulation Of Cytokine Production Involved In Immune Response
Triglyceride Metabolic Process
Phosphatidylcholine Biosynthetic Process
Cholesterol Metabolic Process
Phospholipid Catabolic Process
Response To Glucose
Positive Regulation Of Cholesterol Esterification
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Viral Process
Protein Oxidation
Peptidyl-methionine Modification
Regulation Of Lipid Metabolic Process
Cholesterol Transport
Regulation Of Protein Stability
Negative Regulation Of Cholesterol Transport
Positive Regulation Of Interleukin-8 Production
Cholesterol Efflux
Phospholipid Efflux
Triglyceride-rich Lipoprotein Particle Remodeling
Chylomicron Remodeling
Low-density Lipoprotein Particle Remodeling
High-density Lipoprotein Particle Remodeling
Chylomicron Assembly
High-density Lipoprotein Particle Assembly
High-density Lipoprotein Particle Clearance
Lipoprotein Metabolic Process
Cholesterol Homeostasis
Post-translational Protein Modification
Reverse Cholesterol Transport
Cellular Protein Metabolic Process
Diacylglycerol Catabolic Process
Positive Regulation Of Phagocytosis
Protein Stabilization
Negative Regulation Of Lipid Catabolic Process
Positive Regulation Of Lipid Catabolic Process
Negative Regulation Of Lipase Activity
Negative Regulation Of Cholesterol Import
Negative Regulation Of Cholesterol Transporter Activity
Intermembrane Lipid Transfer
Pathways
Stimuli-sensing channels
Neutrophil degranulation
PPARA activates gene expression
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron assembly
Chylomicron remodeling
Retinoid metabolism and transport
Retinoid metabolism and transport
Drugs
Zinc
Copper
Zinc acetate
Diseases
Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
Familial amyloidosis
GWAS
Interacting Genes
81 interacting genes:
AIG1
APOA2
ASIC1
ASIC2
ASIC3
ATP1B3
ATP6V0B
ATP6V0C
BCL2L2
BNIP1
C2
C3orf52
CFHR5
CHST1
CLDN19
CLRN2
CMTM5
CNIH3
CTXN3
CYB5B
CYB5R3
DAGLA
DVL3
EMP1
ERG28
FAXDC2
FUNDC2
GIMAP1
GIMAP5
GPR25
GPR37L1
GRM2
HMOX2
KCNK1
KTN1
LANCL1
LNPEP
MGLL
MMP14
NKG7
ORMDL1
PEDS1-UBE2V1
PEMT
PGA4
PMP22
PTCH1
RPL13A
RPRM
RTP2
RUVBL1
RUVBL2
SCD
SELENOK
SERP2
SFT2D1
SFT2D2
SFXN1
SFXN5
SLC2A1
SLC35B4
SMCO4
STX6
TECR
THSD7B
TMEM109
TMEM120B
TMEM140
TMEM14B
TMEM203
TMEM208
TMEM254
TMEM60
TMEM86B
TMEM98
TMPO
TNF
TNFRSF10C
TSPO2
VAMP4
WFDC2
YIPF6
31 interacting genes:
ABCA13
APOA1
APOC1
APOD
APOF
AQP6
C4A
CATSPER1
CIAO2A
CREB3
CYBC1
GET1
GJA8
HSD17B13
KIR2DL3
LMNA
MUC1
NAXE
NDRG1
PANX1
PDZK1IP1
PLTP
PSCA
SCARB1
SLC7A1
SSMEM1
STOM
TMEM45A
TMEM82
TREM2
VKORC1
Entrez ID
2040
336
HPRD ID
00585
00129
Ensembl ID
ENSG00000148175
ENSG00000158874
Uniprot IDs
A0A024R882
F8VSL7
P27105
P02652
PDB IDs
Enriched GO Terms of Interacting Partners
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