STOM and PEMT

Data Source:
BioGRID (two hybrid)

		STOM	PEMT
Description		stomatin	phosphatidylethanolamine N-methyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Endoplasmic Reticulum Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Mitochondrial Membrane Sarcolemma Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Phosphatidyl-N-methylethanolamine N-methyltransferase Activity Phosphatidylethanolamine N-methyltransferase Activity Phosphatidylethanolamine Binding Phosphatidyl-N-dimethylethanolamine N-methyltransferase Activity
	Biological Process	Neutrophil Degranulation Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Protein Targeting To Membrane Regulation Of Acid-sensing Ion Channel Activity	Blastocyst Hatching Phosphatidylcholine Biosynthetic Process Sphingomyelin Biosynthetic Process Negative Regulation Of Cell Population Proliferation Methylation Response To Vitamin Response To Drug Response To Amino Acid Response To Ethanol S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Positive Regulation Of Lipoprotein Metabolic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		Stimuli-sensing channels Neutrophil degranulation	Synthesis of PC
Drugs
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS			Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Obsessive-compulsive symptoms ( 26859814) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Waist-hip ratio ( 28552196 25673412) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (recessive genetic model) ( 30778226) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		81 interacting genes: AIG1 APOA2 ASIC1 ASIC2 ASIC3 ATP1B3 ATP6V0B ATP6V0C BCL2L2 BNIP1 C2 C3orf52 CFHR5 CHST1 CLDN19 CLRN2 CMTM5 CNIH3 CTXN3 CYB5B CYB5R3 DAGLA DVL3 EMP1 ERG28 FAXDC2 FUNDC2 GIMAP1 GIMAP5 GPR25 GPR37L1 GRM2 HMOX2 KCNK1 KTN1 LANCL1 LNPEP MGLL MMP14 NKG7 ORMDL1 PEDS1-UBE2V1 PEMT PGA4 PMP22 PTCH1 RPL13A RPRM RTP2 RUVBL1 RUVBL2 SCD SELENOK SERP2 SFT2D1 SFT2D2 SFXN1 SFXN5 SLC2A1 SLC35B4 SMCO4 STX6 TECR THSD7B TMEM109 TMEM120B TMEM140 TMEM14B TMEM203 TMEM208 TMEM254 TMEM60 TMEM86B TMEM98 TMPO TNF TNFRSF10C TSPO2 VAMP4 WFDC2 YIPF6	4 interacting genes: AQP6 FCER1G SPP1 STOM
Entrez ID		2040	10400
HPRD ID		00585	03862
Ensembl ID		ENSG00000148175	ENSG00000133027
Uniprot IDs		A0A024R882 F8VSL7 P27105	Q9UBM1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?