GPS1 and SENP8

		GPS1	SENP8
Description		G protein pathway suppressor 1	SUMO peptidase family member, NEDD8 specific
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GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Cytosol
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Protein Binding NEDD8-specific Protease Activity
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Protein Deubiquitination Post-translational Protein Modification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	UCH proteinases Neddylation
Drugs
Diseases
GWAS			Metabolite levels (HVA/MHPG ratio) ( 23319000)
Interacting Genes		29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	15 interacting genes: CHN2 COPS2 CUL1 CUL2 CUL4A GPS1 HSPA4 NEDD8 PLA2G2A SMURF1 TERF1 UBE2M USP15 USP21 USP28
Entrez ID		2873	123228
HPRD ID		15991	09784
Ensembl ID		ENSG00000169727	ENSG00000166192
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	A8K8D3 Q96LD8
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	1XT9 2BKQ 2BKR
Enriched GO Terms of Interacting Partners?
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