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GPS1

Description G protein pathway suppressor 1
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
  • COP9 Signalosome
Molecular Function
  • GTPase Inhibitor Activity
  • Protein Binding
Biological Process
  • Inactivation Of MAPK Activity
  • Protein Deneddylation
  • Nucleotide-excision Repair, DNA Damage Recognition
  • Transcription-coupled Nucleotide-excision Repair
  • JNK Cascade
  • Negative Regulation Of GTPase Activity
  • Post-translational Protein Modification
Pathways
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
Drugs
Diseases
GWAS
Interacting Genes 29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL
Entrez ID 2873
HPRD ID 15991
Ensembl ID ENSG00000169727
Uniprot IDs A0A096LP07 A0A096LPJ3 C9JFE4 Q13098
PDB IDs 4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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