TRIM59 and RASSF3

Data Source:
BioGRID (two hybrid)

		TRIM59	RASSF3
Description		tripartite motif containing 59	Ras association domain family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B	Cytoplasm Cytosol Microtubule Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Signal Transduction Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Cardiometabolic and hematological traits ( 27668658) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 30804560) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Prostate cancer ( 29892016) Resting heart rate ( 29769521 27798624)
Interacting Genes		26 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PLLP RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22	14 interacting genes: APP CBX8 DAXX FAM110A ITPRIP KDM1A KYNU LITAF PARD6B RPRD1B TENT5D TFRC TRIM59 ZNF410
Entrez ID		286827	283349
HPRD ID		15568	08448
Ensembl ID		ENSG00000213186	ENSG00000153179
Uniprot IDs		Q8IWR1	Q86WH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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