TRIM59 and ANKRD33

Data Source:
BioGRID (two hybrid)

		TRIM59	ANKRD33
Description		tripartite motif containing 59	ankyrin repeat domain 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B	Nucleus Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Energy intake ( 30071075) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Serum uric acid levels ( 30993211)
Interacting Genes		26 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PLLP RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22	11 interacting genes: ANKRD11 BFSP2 GPSM3 HPCAL4 KLHL42 MBD3 SDCBP TLX3 TRIM59 UBQLN2 USHBP1
Entrez ID		286827	341405
HPRD ID		15568	12465
Ensembl ID		ENSG00000213186	ENSG00000167612
Uniprot IDs		Q8IWR1	Q0VAA8 Q5K617 Q7Z3H0
PDB IDs
Enriched GO Terms of Interacting Partners?
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