RASSF3 and TRIM59

Data Source:
BioGRID (two hybrid)

		RASSF3	TRIM59
Description		Ras association domain family member 3	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Signal Transduction Regulation Of Apoptotic Process	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 30804560) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Prostate cancer ( 29892016) Resting heart rate ( 29769521 27798624)	Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		14 interacting genes: APP CBX8 DAXX FAM110A ITPRIP KDM1A KYNU LITAF PARD6B RPRD1B TENT5D TFRC TRIM59 ZNF410	26 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PLLP RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		283349	286827
HPRD ID		08448	15568
Ensembl ID		ENSG00000153179	ENSG00000213186
Uniprot IDs		Q86WH2	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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