TRIM59 and SNAP47

Data Source:
BioGRID (two hybrid)

		TRIM59	SNAP47
Description		tripartite motif containing 59	synaptosome associated protein 47
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B	Plasma Membrane Endomembrane System BLOC-1 Complex SNARE Complex Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Exocytosis Vesicle Fusion Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)	Height ( 28552196) Night sleep phenotypes ( 27126917)
Interacting Genes		26 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PLLP RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22	23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59
Entrez ID		286827	116841
HPRD ID		15568	17148
Ensembl ID		ENSG00000213186	ENSG00000143740
Uniprot IDs		Q8IWR1	A0A087X0B7 Q5SQN1
PDB IDs
Enriched GO Terms of Interacting Partners?
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