SNAP47 and LRRC4C

Data Source:
BioGRID (two hybrid)

		SNAP47	LRRC4C
Description		synaptosome associated protein 47	leucine rich repeat containing 4C
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System BLOC-1 Complex SNARE Complex Perinuclear Region Of Cytoplasm Presynapse	Extracellular Space Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Exocytosis Vesicle Fusion Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Night sleep phenotypes ( 27126917)	Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59	28 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TWSG1 VEZT VSTM1 WHRN YIPF6
Entrez ID		116841	57689
HPRD ID		17148	12303
Ensembl ID		ENSG00000143740	ENSG00000148948
Uniprot IDs		A0A087X0B7 Q5SQN1	Q4JIV9 Q4JIW0 Q9HCJ2
PDB IDs			3ZYJ
Enriched GO Terms of Interacting Partners?
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