GPR35 and PPP1R3F

Data Source:
BioGRID (two hybrid)

		GPR35	PPP1R3F
Description		G protein-coupled receptor 35	protein phosphatase 1 regulatory subunit 3F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Protein Phosphatase Type 1 Complex Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity C-X-C Chemokine Receptor Activity	Protein Phosphatase 1 Binding Protein Phosphatase Binding Glycogen Binding
	Biological Process	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Chemokine-mediated Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Neuronal Action Potential	Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen (starch) Synthase Activity
Pathways		Class A/1 (Rhodopsin-like receptors)
Drugs		Furosemide Pyrantel Kynurenic Acid
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 25489960) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Sclerosing cholangitis and ulcerative colitis (combined) ( 22821403) Ulcerative colitis ( 28067908 21297633)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		59 interacting genes: ABHD14A ADGRB1 AIG1 APH1A ATP1A1 ATP2C1 AUP1 B3GAT3 B4GALT2 BNIP1 CANX CD81 CH25H CMTM3 CRHR2 ERGIC3 FLRT1 FTH1 GHITM GJC2 GPR146 GPR161 HLA-A KCNJ4 KDELR1 LSS MCOLN1 MSMO1 NPC1 NSDHL OSTC PLD3 PLLP PLXDC1 PPP1R3F RTN3 RTN4 SCARB1 SDHD SELENOK SLC15A4 SLC2A1 SLC31A2 SLC37A1 SLC37A4 SLC45A4 SLC8A2 SLC9A7 SPART SYNGR2 SYT11 TMEM161A TMEM94 TSPAN7 VPS25 VTI1B YIF1B ZDHHC3 ZFAND1	4 interacting genes: AGTR1 GPR35 HTR2B PTGER4
Entrez ID		2859	89801
HPRD ID		16003	15170
Ensembl ID		ENSG00000178623	ENSG00000049769
Uniprot IDs		A8K2J1 B2RA17 Q9HC97	Q0D2I0 Q6ZSY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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