RRP1B and LSM1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RRP1B	LSM1
Description		ribosomal RNA processing 1B	LSM1 homolog, mRNA degradation associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Preribosome, Large Subunit Precursor Preribosome, Small Subunit Precursor	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	RRNA Processing MRNA Processing Apoptotic Process RNA Splicing Negative Regulation Of Phosphatase Activity Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of RNA Splicing Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Diastolic blood pressure ( 28135244 27618447) Mean corpuscular hemoglobin ( 27863252) Refractive error ( 32231278) Systolic blood pressure ( 27618447)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		4 interacting genes: CSNK2A1 LSM1 PPP1CC SRPK2	32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		23076	27257
HPRD ID		10009	06281
Ensembl ID		ENSG00000160208	ENSG00000175324
Uniprot IDs		Q14684	A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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