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RNF115 and ATN1
Data Source:
BioGRID
(two hybrid)
RNF115
ATN1
Description
ring finger protein 115
atrophin 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Cell Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Transcription Factor Binding
Transcription Corepressor Activity
Protein Binding
Protein Domain Specific Binding
Biological Process
Protein Polyubiquitination
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Negative Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Neuron Apoptotic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Regulation of PTEN gene transcription
Drugs
Diseases
Dentatorubropallidoluysian atrophy (DRPLA)
GWAS
Apolipoprotein A1 levels (
32203549
)
Breast cancer (
25751625
29059683
)
HDL cholesterol levels (
32203549
)
Platelet distribution width (
32888494
)
Refractive error (
32231278
)
Interacting Genes
32 interacting genes:
AKT1
APP
ATN1
CDK10
CST3
DAZAP2
DOCK4
EGFR
FOLR3
HRAS
IGHA1
MDM4
MFAP4
NFKBIA
RAB7A
RAD23A
RPL18A
TTR
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2I
UBE2N
UBE2W
USP9X
VCP
ZNRD2
121 interacting genes:
AGRN
ALG13
ARF3
ATRX
BAG3
BAG6
BAIAP2
CACNB1
CASP1
CASP3
CBFA2T2
CENPJ
CHRD
CRACR2A
CRIP2
CSNK2A1
CTNND2
DGCR6L
DMPK
DMRT3
DVL1
DVL2
ECM1
EFEMP1
EFEMP2
ETNK2
EWSR1
FBLN1
FBLN2
FBLN5
GAPDH
GCC1
GIGYF1
GRN
HGS
HINFP
HNRNPF
HSPG2
ITCH
JAG2
KAT6A
KAT6B
KAT7
KRT31
KRTAP12-2
KRTAP15-1
KRTAP19-2
KRTAP19-5
KRTAP4-12
KRTAP6-2
KRTAP9-3
LENG8
LRP2
LTBP1
LTBP4
LYST
MAGI1
MAGI2
MAP7D1
MBP
MDFI
MEGF11
MEGF6
MEGF8
NCK2
NELL1
NELL2
NOC2L
NR2E1
OLIG3
P4HA3
PCSK5
PDCD6IP
PFKL
PIN1
PITX1
PITX2
PLSCR1
PPP1R32
PRRC2A
PRRC2B
PSMA3
PSME3
RAD54L2
RBFOX1
RBFOX2
RBM10
RBM14
RBM4B
RBPMS
RCHY1
RERE
RHOXF2
RNF115
RNF31
RUNX1T1
SH3RF1
SIAH1
SIAH2
SLC25A48
SLIT1
SPAG5
SS18L1
SSPOP
STXBP4
SYVN1
TEKT3
TEP1
TLE1
TLE5
TNFAIP8
TRIP6
USP2
USP54
VIM
WDR5
WWP1
WWP2
ZMYND8
ZNF503
ZSWIM8
Entrez ID
27246
1822
HPRD ID
18328
06311
Ensembl ID
ENSG00000265491
ENSG00000111676
Uniprot IDs
Q9Y4L5
P54259
Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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