SERP1 and CYBRD1

Data Source:
BioGRID (two hybrid)

		SERP1	CYBRD1
Description		stress associated endoplasmic reticulum protein 1	cytochrome b reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Protein Transport Endoplasmic Reticulum Unfolded Protein Response IRE1-mediated Unfolded Protein Response	Cellular Iron Ion Homeostasis Response To Iron Ion
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Iron uptake and transport
Drugs
Diseases
GWAS			Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Pulse pressure ( 30224653)
Interacting Genes		52 interacting genes: ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1
Entrez ID		27230	79901
HPRD ID		18037	05764
Ensembl ID		ENSG00000120742	ENSG00000071967
Uniprot IDs		Q9Y6X1	Q53TN4
PDB IDs			5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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