CYBRD1 and FKBP8

Data Source:
BioGRID (two hybrid)

		CYBRD1	FKBP8
Description		cytochrome b reductase 1	FKBP prolyl isomerase 8
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GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Brush Border Membrane Extracellular Exosome	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding
	Biological Process	Cellular Iron Ion Homeostasis Response To Iron Ion	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Regulation Of Gene Expression Viral Process Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process
Pathways		Iron uptake and transport	Ub-specific processing proteases
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Pulse pressure ( 30224653)	Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1	48 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1
Entrez ID		79901	23770
HPRD ID		05764	05327
Ensembl ID		ENSG00000071967	ENSG00000105701
Uniprot IDs		Q53TN4	A0A024R7P2 B2R8G6 Q14318
PDB IDs		5ZLE 5ZLG	2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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