SERP1 and BIK

Data Source:
BioGRID (two hybrid)

		SERP1	BIK
Description		stress associated endoplasmic reticulum protein 1	BCL2 interacting killer
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Protein Transport Endoplasmic Reticulum Unfolded Protein Response IRE1-mediated Unfolded Protein Response	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS			Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		52 interacting genes: ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	95 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBE2D1 UBIAD1 VAMP3 VAMP5 ZFPL1
Entrez ID		27230	638
HPRD ID		18037	04547
Ensembl ID		ENSG00000120742	ENSG00000100290
Uniprot IDs		Q9Y6X1	A0A024R4X6 Q13323
PDB IDs			2IPE
Enriched GO Terms of Interacting Partners?
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