SERP1 and TNFRSF9

Data Source:
BioGRID (two hybrid)

		SERP1	TNFRSF9
Description		stress associated endoplasmic reticulum protein 1	TNF receptor superfamily member 9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Protein Transport Endoplasmic Reticulum Unfolded Protein Response IRE1-mediated Unfolded Protein Response	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	TNFs bind their physiological receptors
Drugs			Urelumab
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		52 interacting genes: ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MFSD14B MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A6 SLC22A1 SLC22A2 SLC35C2 SSMEM1 STX1A STX2 STX4 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		27230	3604
HPRD ID		18037	03767
Ensembl ID		ENSG00000120742	ENSG00000049249
Uniprot IDs		Q9Y6X1	Q07011
PDB IDs			6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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