AP3M1 and RUFY1

Data Source:
BioGRID (pull down)

		AP3M1	RUFY1
Description		adaptor related protein complex 3 subunit mu 1	RUN and FYVE domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		26985	80230
HPRD ID		16496	15282
Ensembl ID		ENSG00000185009	ENSG00000176783
Uniprot IDs		A0A024QZR5 B4DRN6 Q9Y2T2	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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