AP3M1 and IL36RN

Data Source:
BioGRID (two hybrid)

		AP3M1	IL36RN
Description		adaptor related protein complex 3 subunit mu 1	interleukin 36 receptor antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding
	Biological Process	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Interleukin-36 pathway
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)	Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)
Interacting Genes		15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9	18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B
Entrez ID		26985	26525
HPRD ID		16496	16112
Ensembl ID		ENSG00000185009	ENSG00000136695
Uniprot IDs		A0A024QZR5 B4DRN6 Q9Y2T2	A0A024R518 Q9UBH0
PDB IDs			4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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